Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.500 Therapeutic phenotype CTD_human Effects of quercetin on gene and protein expression of NOX and NOS after myocardial ischemia and reperfusion in rabbit. 19207477 2009
Entrez Id: 581
Gene Symbol: BAX
BAX 		0.500 Biomarker phenotype CTD_human Cardioprotective effects of benazepril, an angiotensin-converting enzyme inhibitor, in an ischaemia-reperfusion model of myocardial infarction in rats. 20026869 2009
Entrez Id: 6652
Gene Symbol: SORD
SORD 		0.500 Biomarker phenotype CTD_human Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart. 18549825 2008
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.500 Biomarker phenotype RGD Role of endogenous endothelin-1 in post-ischemic cardiac dysfunction and norepinephrine overflow in rat hearts. 18586023 2008
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		0.500 Biomarker phenotype RGD Antiapoptosis and mitochondrial effect of pioglitazone preconditioning in the ischemic/reperfused heart of rat. 18470603 2008
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.500 Biomarker phenotype RGD Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart. 18390819 2008
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		0.500 Biomarker phenotype CTD_human Polyol pathway mediates iron-induced oxidative injury in ischemic-reperfused rat heart. 18549825 2008
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1 		0.500 Biomarker phenotype RGD Diastolic Ca2+ overload caused by Na+/Ca2+ exchanger during the first minutes of reperfusion results in continued myocardial stunning. 17822695 2007
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1 		0.500 Biomarker phenotype RGD Chronic intermittent hypoxia alters Ca2+ handling in rat cardiomyocytes by augmented Na+/Ca2+ exchange and ryanodine receptor activities in ischemia-reperfusion. 17267548 2007
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1 		0.500 Biomarker phenotype RGD Effects of landiolol on mechanical and metabolic changes in rat reperfused ischaemic hearts. 17201736 2007
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.500 Biomarker phenotype CTD_human Cardioprotective effects of bosentan, a mixed endothelin type A and B receptor antagonist, during myocardial ischaemia and reperfusion in rats. 16700825 2006
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.500 Biomarker phenotype CTD_human Different contributions of endothelin-A and endothelin-B receptors in postischemic cardiac dysfunction and norepinephrine overflow in rat hearts. 15642760 2005
Entrez Id: 100506742
Gene Symbol: CASP12
CASP12 		0.500 Biomarker phenotype CTD_human Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO. 14998631 2004
Entrez Id: 6546
Gene Symbol: SLC8A1
SLC8A1 		0.500 Biomarker phenotype CTD_human Cardioprotective effect of SEA0400, a selective inhibitor of the Na(+)/Ca(2+) exchanger, on myocardial ischemia-reperfusion injury in rats. 15215644 2004
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.500 Therapeutic phenotype CTD_human Resveratrol protects myocardial ischemia-reperfusion injury through both NO-dependent and NO-independent mechanisms. 14990356 2004
Entrez Id: 840
Gene Symbol: CASP7
CASP7 		0.500 Biomarker phenotype CTD_human Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO. 14998631 2004
Entrez Id: 842
Gene Symbol: CASP9
CASP9 		0.500 Biomarker phenotype CTD_human Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO. 14998631 2004
Entrez Id: 841
Gene Symbol: CASP8
CASP8 		0.500 Biomarker phenotype CTD_human Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO. 14998631 2004
Entrez Id: 836
Gene Symbol: CASP3
CASP3 		0.500 Biomarker phenotype CTD_human Minocycline inhibits caspase activation and reactivation, increases the ratio of XIAP to smac/DIABLO, and reduces the mitochondrial leakage of cytochrome C and smac/DIABLO. 14998631 2004
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.500 Biomarker phenotype CTD_human Resveratrol protects myocardial ischemia-reperfusion injury through both NO-dependent and NO-independent mechanisms. 14990356 2004
Entrez Id: 6652
Gene Symbol: SORD
SORD 		0.500 Biomarker phenotype RGD Sorbitol dehydrogenase: a novel target for adjunctive protection of ischemic myocardium. 14525943 2003
Entrez Id: 6403
Gene Symbol: SELP
SELP 		0.500 Biomarker phenotype CTD_human Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. 12087064 2002
Entrez Id: 3091
Gene Symbol: HIF1A
HIF1A 		0.500 Biomarker phenotype RGD Myocardial infarction in diabetic rats: role of hyperglycaemia on infarct size and early expression of hypoxia-inducible factor 1. 12189448 2002
Entrez Id: 4843
Gene Symbol: NOS2
NOS2 		0.500 Biomarker phenotype CTD_human Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. 12087064 2002
Entrez Id: 6347
Gene Symbol: CCL2
CCL2 		0.500 Biomarker phenotype CTD_human Ligands of the peroxisome proliferator-activated receptors (PPAR-gamma and PPAR-alpha) reduce myocardial infarct size. 12087064 2002