×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
CTD_human
Effects of pharmacological agents on the lifespan phenotype of Drosophila DJ-1beta mutants.
20423725
2010
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
BEFREE
Mutations of the DJ-1 (PARK7 ) gene are linked to familial Parkinson's disease .
15784737
2005
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
LHGDN
Mitochondrial localization of the Parkinson's disease related protein DJ-1 : implications for pathogenesis.
15944198
2005
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
LHGDN
DJ-1/PARK7 , a cancer- and Parkinson's disease (PD )-associated protein, protects cells from toxic stresses.
17015834
2006
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
BEFREE
Mutations in the DJ-1 gene cause autosomal recessive early onset PD in two European families.
14713311
2003
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
LHGDN
Molecular basis for the structural instability of human DJ-1 induced by the L166P mutation associated with Parkinson's disease.
18707128
2008
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
BEFREE
DJ-1 (PARK7 ) is a gene linked to autosomal recessive Parkinson disease (PD ).
24899725
2014
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
BEFREE
Mutations in the DJ-1 gene have been implicated in the PARK7 -linked autosomal recessive form of Parkinson's disease (PD ).
15519239
2004
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
LHGDN
[Association of the DJ-1 gene polymorphism with sporadic Parkinson's disease in Sichuan province of China].
18841573
2008
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
BEFREE
We characterized the pathophenotypes of dopaminergic neuronal cells that were deficient in PINK1 or DJ-1 , genes with mutations linked to familial PD .
21664494
2011
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
BEFREE
DJ-1 - a causative agent of familial Parkinson's disease PARK7 - is responsible for inducing antioxidative reaction.
20202083
2010
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
BEFREE
Mutations in seven genes are robustly associated with autosomal dominant (SNCA, LRRK2, EIF4G1, VPS35) or recessive (parkin/PARK2, PINK1, DJ1/PARK7 ) Parkinson's disease (PD ) or parkinsonism.
23462481
2013
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
BEFREE
Our aim was to examine the possibility of using DJ-1 (PARK7 ), as a novel therapeutic target for Parkinson's disease .
26024237
2015
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
LHGDN
Genetics of Parkinson disease.
15717024
2004
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
LHGDN
Novel homozygous p.E64D mutation in DJ1 in early onset Parkinson disease (PARK7).
15365989
2004
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
LHGDN
L166P mutant DJ-1, causative for recessive Parkinson's disease, is degraded through the ubiquitin-proteasome system.
12851414
2003
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
BEFREE
Elucidating the physiological role of DJ-1 protein may promote understanding of the mechanisms of brain neuronal maintenance and pathogenesis of Parkinson's disease .
12446870
2003
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
CTD_human
Correlation between the biochemical pathways altered by mutated parkinson-related genes and chronic exposure to manganese.
25149416
2014
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
BEFREE
However, the causes of the emotional symptom accompanying PARK7 -associated and other forms of Parkinson's disease remain largely unexplored.
31504219
2019
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
GeneticVariation
disease
BEFREE
DJ-1 (also known as PARK7 ) has been identified as a causal gene for hereditary recessive Parkinson's disease (PD ).
28993701
2017
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
BEFREE
Loss-of-function of DJ-1 protein is suggested to contribute to the onset of PD , but the causes of DJ-1 dysfunction remain insufficiently elucidated.
28446034
2017
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
BEFREE
Here, DJ-1 (PARK7 ) gained major attention when a conserved cysteine residue with a putative role in oxidative stress sensing/protection was linked to PD .
30011180
2018
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
AlteredExpression
disease
BEFREE
Heightened DJ-1 (Park7 ) expression is associated with a reduction in chemotherapeutic-induced cell death and poor prognosis in several cancers, whereas the loss of DJ-1 function is found in a subgroup of Parkinson disease associated with neuronal death.
21097510
2011
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
BEFREE
DJ-1 was initially identified by us as a novel oncogene and has recently been found to be a causative gene for familial Parkinson's disease PARK7 .
16781058
2006
×
Entrez Id:
11315
Gene Symbol:
PARK7
PARK7
0.600
Biomarker
disease
BEFREE
The DJ-1 gene is a causative gene for familial PD (park7) and also an oncogene.
23766857
2013