×
Entrez Id: 7533
Gene Symbol: YWHAH
YWHAH
0.300
Therapeutic
group
CTD_human
14-3-3 protein regulates Ask1 signaling and protects against diabetic cardiomyopathy.
18342293 2008
×
Entrez Id: 165904
Gene Symbol: XIRP1
XIRP1
0.010
AlteredExpression
group
BEFREE
Abnormal CMYA1 expression may be involved in cardiac dysplasia and primary cardiomyopathy .
29176328 2017
×
Entrez Id: 7498
Gene Symbol: XDH
XDH
0.200
Therapeutic
group
RGD
Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system.
25889404 2015
×
Entrez Id: 7498
Gene Symbol: XDH
XDH
0.200
Therapeutic
group
RGD
The xanthine oxidase inhibitor oxypurinol reduces cancer cachexia-induced cardiomyopathy.
23751350 2013
×
Entrez Id: 2837
Gene Symbol: UTS2R
UTS2R
0.200
Biomarker
group
RGD
Elevated expression of urotensin II and its receptor in diabetic cardiomyopathy.
18280445 2008
×
Entrez Id: 10911
Gene Symbol: UTS2
UTS2
0.200
Biomarker
group
RGD
Elevated expression of urotensin II and its receptor in diabetic cardiomyopathy.
18280445 2008
×
Entrez Id: 7295
Gene Symbol: TXN
TXN
0.200
Therapeutic
group
CTD_mouse
Overexpression of thioredoxin-1 in transgenic mice attenuates adriamycin-induced cardiotoxicity.
12221060 2002
×
Entrez Id: 7276
Gene Symbol: TTR
TTR
0.010
AlteredExpression
group
BEFREE
Genes encoding desmoglein 2 ( Dsg2) and transthyretin ( Ttr) were significantly differentially expressed at all ages in the HHR, but only Ttr was also differentially expressed in human idiopathic cardiomyopathy .
29775428 2018
×
Entrez Id: 84676
Gene Symbol: TRIM63
TRIM63
0.300
Therapeutic
group
CTD_human
Muscle ring finger 1 mediates cardiac atrophy in vivo.
19168726 2009
×
Entrez Id: 7157
Gene Symbol: TP53
TP53
0.200
Biomarker
group
CTD_mouse
Targeted disruption of p53 attenuates doxorubicin-induced cardiac toxicity in mice.
16013437 2005
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
0.300
Biomarker
group
CTD_human
Troponin-T and brain natriuretic peptide as predictors for adriamycin-induced cardiomyopathy in rats.
14745153 2004
×
Entrez Id: 7139
Gene Symbol: TNNT2
TNNT2
0.300
Biomarker
group
CTD_human
In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity.
17587482 2007
×
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.310
Biomarker
group
BEFREE
TNNI3 is the third most important disease gene in this cohort and complete loss of TNNI3 leads to severe pediatric CMP .31568572 2019
×
Entrez Id: 7137
Gene Symbol: TNNI3
TNNI3
0.310
Biomarker
group
CTD_human
In vitro and in vivo examination of cardiac troponins as biochemical markers of drug-induced cardiotoxicity.
17587482 2007
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.510
Biomarker
group
CTD_human
Peripartum cardiomyopathy: analysis of clinical outcome, left ventricular function, plasma levels of cytokines and Fas/APO-1.
10716473 2000
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.510
Therapeutic
group
RGD
Antioxidants and tumor necrosis factor alpha-inhibiting activity of sesame oil against doxorubicin-induced cardiotoxicity.
24441175 2014
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.510
GeneticVariation
group
BEFREE
T-cells from CHF patients showed enhanced gene expression of chemokines, ligands in the tumor necrosis factor superfamily, as well as the inflammatory cytokines interferon-gamma and interleukin-18 with similar pattern in ischemic (n=5) and idiopathic cardiomyopathy (n=9).
14522416 2003
×
Entrez Id: 54968
Gene Symbol: TMEM70
TMEM70
0.300
Biomarker
group
CTD_human
TMEM70 mutations cause isolated ATP synthase deficiency and neonatal mitochondrial encephalocardiomyopathy.
18953340 2008
×
Entrez Id: 7097
Gene Symbol: TLR2
TLR2
0.300
Biomarker
group
CTD_human
Modulation of doxorubicin-induced cardiac dysfunction in toll-like receptor-2-knockout mice.
15505089 2004
×
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
0.200
Biomarker
group
RGD
The roles of MMP-2/TIMP-2 in extracellular matrix remodelling in the hearts of STZ-induced diabetic rats.
17982970 2007
×
Entrez Id: 7066
Gene Symbol: THPO
THPO
0.300
Therapeutic
group
CTD_human
Thrombopoietin protects against in vitro and in vivo cardiotoxicity induced by doxorubicin.
16651473 2006
×
Entrez Id: 6901
Gene Symbol: TAZ
TAZ
0.010
GeneticVariation
group
BEFREE
TAZ mutations were found in 4/114 (3.5%) male patients with primary cardiomyopathy .28183324 2017
×
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.300
Therapeutic
group
CTD_human
Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress.
24448315 2014
×
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.300
Biomarker
group
CTD_human
Opposing roles of Akt and STAT3 in the protection of the maternal heart from peripartum stress.
24448315 2014
×
Entrez Id: 6774
Gene Symbol: STAT3
STAT3
0.300
Therapeutic
group
CTD_human
Signal transducer and activator of transcription 3 in the heart transduces not only a hypertrophic signal but a protective signal against doxorubicin-induced cardiomyopathy.
10618415 2000