Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 776
Gene Symbol: CACNA1D
CACNA1D 		0.300 Biomarker disease CTD_human G protein-gated IKACh channels as therapeutic targets for treatment of sick sinus syndrome and heart block. 26831068 2016
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE CALR, JAK2<sup>V617F</sup> and thrombopoietin receptor gene (MPL) mutations were analysed in a test cohort that included 312 patients with SVT. 28483676 2017
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE This meta-analysis provides new evidence supporting the conclusion that the JAK2 46/1 haplotype enrichment is significantly associated with the development of MPNs and SVT in these patients. 25015051 2014
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE Recent research has demonstrated in patients with MPN the existence of factors increasing the risk of SVT such as the presence of the JAK2 V617F mutation and its 46/1 haplotype. 23855810 2013
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE If confirmed in other studies, re-evaluation for JAK2 V617F mutation may be of help in early MPN detection and clinical management of SVT patients. 23916380 2013
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE In addition, our findings in JAK2(V617F)-negative SVT patients indicate an important role for the 46/1 haplotype in the etiology and diagnosis of SVT-related MPNs, independent of JAK2(V617F), that requires further exploration. 21364191 2011
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE In this study, the authors investigated the prevalence of MPN and JAK2 V617F mutation in Korean patients with SVT. 21435189 2011
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE We aimed to study patients with splanchnic vein thrombosis (SVT) and cerebral vein thrombosis (CVT) searching for JAK2 mutations. 21893442 2011
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE Anticoagulation is the treatment of choice for all SVT and proper treatment of the MPD is recommended in patients with SVT associated with the JAK2(V617F) mutation. 19478480 2009
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE JAK2 mutation was associated with increased risk of SVT (odds ratio, 53.98; 95% confidence interval, 13.10-222.45). 19273837 2009
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE We assessed the diagnostic and prognostic value of JAK2 and MPL515 mutations in 241 SVT patients (104 BCS, 137 PVT). 18250227 2008
Entrez Id: 3717
Gene Symbol: JAK2
JAK2 		0.100 GeneticVariation disease BEFREE Anticoagulation therapy combined with low-dose aspirin and proper treatment of the MPD is recommended in patients with SVT associated with the JAK2(V617F) mutation. 17687555 2007
Entrez Id: 10060
Gene Symbol: ABCC9
ABCC9 		0.100 Biomarker disease HPO
Entrez Id: 54795
Gene Symbol: TRPM4
TRPM4 		0.100 Biomarker disease HPO
Entrez Id: 775
Gene Symbol: CACNA1C
CACNA1C 		0.100 Biomarker disease HPO
Entrez Id: 6327
Gene Symbol: SCN2B
SCN2B 		0.100 Biomarker disease HPO
Entrez Id: 783
Gene Symbol: CACNB2
CACNB2 		0.100 Biomarker disease HPO
Entrez Id: 6324
Gene Symbol: SCN1B
SCN1B 		0.100 Biomarker disease HPO
Entrez Id: 8260
Gene Symbol: NAA10
NAA10 		0.100 Biomarker disease HPO
Entrez Id: 6261
Gene Symbol: RYR1
RYR1 		0.100 Biomarker disease HPO
Entrez Id: 6331
Gene Symbol: SCN5A
SCN5A 		0.100 Biomarker disease HPO
Entrez Id: 10021
Gene Symbol: HCN4
HCN4 		0.100 Biomarker disease HPO
Entrez Id: 23171
Gene Symbol: GPD1L
GPD1L 		0.100 Biomarker disease HPO
Entrez Id: 4000
Gene Symbol: LMNA
LMNA 		0.100 Biomarker disease HPO
Entrez Id: 55800
Gene Symbol: SCN3B
SCN3B 		0.100 Biomarker disease HPO