Gene: TP53 ×
Source: CLINVAR ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 GeneticVariation disease CLINVAR Germline mutations in 40 cancer susceptibility genes among Chinese patients with high hereditary risk breast cancer. 29752822 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 GeneticVariation disease CLINVAR Clinical characteristics and registry-validated extended pedigrees of germline TP53 mutation carriers in Denmark. 29324801 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Mutational processes shape the landscape of TP53 mutations in human cancer. 30224644 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Contribution of de novo and mosaic TP53 mutations to Li-Fraumeni syndrome. 29070607 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 GeneticVariation disease CLINVAR Mutational processes shape the landscape of TP53 mutations in human cancer. 30224644 2018
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR The Clinical Utility of Next Generation Sequencing Results in a Community-Based Hereditary Cancer Risk Program. 27276934 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Genomic analysis of inherited breast cancer among Palestinian women: Genetic heterogeneity and a founder mutation in TP53. 28486781 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Li-Fraumeni syndrome presenting as mucosal melanoma: Case report and treatment considerations. 27726232 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 GeneticVariation disease CLINVAR The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation sequencing studies. 28349240 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Recurrent TP53 missense mutation in cancer patients of Arab descent. 27866339 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 GeneticVariation disease CLINVAR Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients. 28724667 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR The Human Gene Mutation Database: towards a comprehensive repository of inherited mutation data for medical research, genetic diagnosis and next-generation sequencing studies. 28349240 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 GeneticVariation disease CLINVAR The frequency of cancer predisposition gene mutations in hereditary breast and ovarian cancer patients in Taiwan: From BRCA1/2 to multi-gene panels. 28961279 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Germline Mutations in Cancer Susceptibility Genes in a Large Series of Unselected Breast Cancer Patients. 28724667 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Germline TP53 mutations result into a constitutive defect of p53 DNA binding and transcriptional response to DNA damage. 28369373 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Synonymous mutation in TP53 results in a cryptic splice site affecting its DNA-binding site in an adolescent with two primary sarcomas. 28475293 2017
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India. 26911350 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families. 26534844 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Genetic and functional analysis of a Li Fraumeni syndrome family in China. 26818906 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 GeneticVariation disease CLINVAR Detection of high frequency of mutations in a breast and/or ovarian cancer cohort: implications of embracing a multi-gene panel in molecular diagnosis in India. 26911350 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Germline TP53 Mutation and Clinical Characteristics of Korean Patients With Li-Fraumeni Syndrome. 27374712 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR TP53 mutations in older adults with acute myeloid leukemia. 26781615 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Pathogenic and likely pathogenic variant prevalence among the first 10,000 patients referred for next-generation cancer panel testing. 26681312 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 CausalMutation disease CLINVAR Biochemical and imaging surveillance in germline TP53 mutation carriers with Li-Fraumeni syndrome: 11 year follow-up of a prospective observational study. 27501770 2016
Entrez Id: 7157
Gene Symbol: TP53
TP53 		1.000 GeneticVariation disease CLINVAR Targeted massively parallel sequencing of a panel of putative breast cancer susceptibility genes in a large cohort of multiple-case breast and ovarian cancer families. 26534844 2016