DisGeNET - a database of gene-disease associations

Li-Fraumeni Syndrome, C0085390

N. genes: 2; N. variants: 157

Source: CLINVAR ×

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Gene

Disease 2

Variant

Source

Semantic type

Disease Class

Type

HPO Term

DO Class

N. genes1

N. genes2

N. of shared genes

Jaccard_g

p-value_g

N. variants1

N. variants2

N. of shared variants

Jaccard_v

p-value_v

Associated Disease

N. genes

N. variants

N. of shared genes

JI_g

p-value_g

N. of shared variants

JI_v

p-value_v

CUI:	C0001418
Disease:	Adenocarcinoma

1

1

1

0.50

1

6.4E-03

CUI:	C0023269
Disease:	leiomyosarcoma

1

1

1

0.50

1

6.4E-03

CUI:	C0029463
Disease:	Osteosarcoma

4

20

2

0.50

6

3.5E-02

CUI:	C0205770
Disease:	Choroid Plexus Papilloma

Choroid Plexus Papilloma

1

7

1

0.50

4

2.5E-02

CUI:	C0238461
Disease:	Anaplastic thyroid carcinoma

Anaplastic thyroid carcinoma

1

1

1

0.50

1

6.4E-03

CUI:	C0334579
Disease:	Anaplastic astrocytoma

Anaplastic astrocytoma

1

2

1

0.50

2

1.3E-02

CUI:	C0334586
Disease:	Pleomorphic Xanthoastrocytoma

Pleomorphic Xanthoastrocytoma

1

1

1

0.50

1

6.4E-03

CUI:	C0346011
Disease:	Fibrofolliculoma

Fibrofolliculoma

1

1

1

0.50

1

6.4E-03

CUI:	C0431109
Disease:	Choroid Plexus Carcinoma

Choroid Plexus Carcinoma

1

1

1

0.50

1

6.4E-03

CUI:	C0578878
Disease:	Inflammation of large intestine

Inflammation of large intestine

1

1

1

0.50

1

6.4E-03

CUI:	C1266184
Disease:	Atypical Teratoid Rhabdoid Tumor

Atypical Teratoid Rhabdoid Tumor

1

1

1

0.50

1

6.4E-03

CUI:	C1328587
Disease:	Panhypogammaglobulinemia

Panhypogammaglobulinemia

1

0

1

0.50

0

0

CUI:	C1835398
Disease:	LI-FRAUMENI SYNDROME 1

LI-FRAUMENI SYNDROME 1

1

39

1

0.50

26

0.15

CUI:	C1836482
Disease:	Li-Fraumeni Syndrome 2

Li-Fraumeni Syndrome 2

1

11

1

0.50

2

1.2E-02

CUI:	C1858433
Disease:	BREAST AND COLORECTAL CANCER, SUSCEPTIBILITY TO

BREAST AND COLORECTAL CANCER, SUSCEPTIBILITY TO

1

7

1

0.50

1

6.1E-03

CUI:	C1858439
Disease:	CANCER OF MULTIPLE TYPES, SUSCEPTIBILITY TO

CANCER OF MULTIPLE TYPES, SUSCEPTIBILITY TO

1

0

1

0.50

0

0

CUI:	C1859972
Disease:	ADRENOCORTICAL CARCINOMA, HEREDITARY

ADRENOCORTICAL CARCINOMA, HEREDITARY

1

6

1

0.50

4

2.5E-02

CUI:	C1859973
Disease:	Adrenocortical Carcinoma, Pediatric

Adrenocortical Carcinoma, Pediatric

1

2

1

0.50

2

1.3E-02

CUI:	C2675080
Disease:	Li-Fraumeni-Like Syndrome

Li-Fraumeni-Like Syndrome

1

5

1

0.50

4

2.5E-02

CUI:	C2698310
Disease:	B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified

B Lymphoblastic Leukemia/Lymphoma, Not Otherwise Specified

1

1

1

0.50

1

6.4E-03

CUI:	C2931822
Disease:	Nasopharyngeal carcinoma

Nasopharyngeal carcinoma

1

6

1

0.50

4

2.5E-02

CUI:	C3553606
Disease:	BASAL CELL CARCINOMA, SUSCEPTIBILITY TO, 7

BASAL CELL CARCINOMA, SUSCEPTIBILITY TO, 7

1

7

1

0.50

4

2.5E-02

CUI:	C3714644
Disease:	Thymus Neoplasms

Thymus Neoplasms

1

0

1

0.50

0

0

CUI:	C4013716
Disease:	Small cell carcinoma of the ovary, hypercalcemic type

Small cell carcinoma of the ovary, hypercalcemic type

1

0

1

0.50

0

0

CUI:	C4748488
Disease:	BONE MARROW FAILURE SYNDROME 5

BONE MARROW FAILURE SYNDROME 5

1

0

1

0.50

0

0