Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7057
Gene Symbol: THBS1
THBS1 		0.210 Biomarker disease MGD Thrombospondin-1 and CD47 regulate blood pressure and cardiac responses to vasoactive stress. 19284971 2009
Entrez Id: 7057
Gene Symbol: THBS1
THBS1 		0.210 Biomarker disease MGD Sjögren's syndrome-like ocular surface disease in thrombospondin-1 deficient mice. 19700744 2009
Entrez Id: 7057
Gene Symbol: THBS1
THBS1 		0.210 Biomarker disease MGD Thrombospondin-1 and CD47 limit cell and tissue survival of radiation injury. 18787106 2008
Entrez Id: 3399
Gene Symbol: ID3
ID3 		0.210 Biomarker disease BEFREE Inhibitor of differentiation 3 (Id3)-deficient mice show sicca symptoms, lymphocyte infiltration of exocrine glands and positive anti-Ro/SSA and anti-La/SSB antibodies, all hallmarks of primary Sjögren's syndrome (pSS). 18296721 2008
Entrez Id: 3399
Gene Symbol: ID3
ID3 		0.210 Biomarker disease MGD A T cell intrinsic role of Id3 in a mouse model for primary Sjogren's syndrome. 15485632 2004
Entrez Id: 7057
Gene Symbol: THBS1
THBS1 		0.210 Biomarker disease BEFREE Finally, no mutations that could be related to sicca syndrome or argue the existence of clinical progression to TSP/HAM were found. 10459164 1999
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.210 Biomarker disease MGD Targeted disruption of the mouse transforming growth factor-beta 1 gene results in multifocal inflammatory disease. 1436033 1992
Entrez Id: 1588
Gene Symbol: CYP19A1
CYP19A1 		0.200 Biomarker disease MGD Aromatase controls Sjögren syndrome-like lesions through monocyte chemotactic protein-1 in target organ and adipose tissue-associated macrophages. 25447050 2015
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.200 Therapeutic disease RGD [Astragalus polysaccharides improved the cardiac function in Sjögren's syndrome model rats based on keap 1-Nrf2/ARE signaling pathway: a mechanism exploration]. 24941846 2014
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.200 Biomarker disease MGD Conditional IL-2 Gene Deletion: Consequences for T Cell Proliferation. 22590468 2012
Entrez Id: 1236
Gene Symbol: CCR7
CCR7 		0.200 Biomarker disease MGD NLRP10 is a NOD-like receptor essential to initiate adaptive immunity by dendritic cells. 22538615 2012
Entrez Id: 4792
Gene Symbol: NFKBIA
NFKBIA 		0.200 Biomarker disease MGD Defective feedback regulation of NF-kappaB underlies Sjogren's syndrome in mice with mutated kappaB enhancers of the IkappaBalpha promoter. 20696914 2010
Entrez Id: 10758
Gene Symbol: TRAF3IP2
TRAF3IP2 		0.200 Biomarker disease MGD Deficiency of Act1, a critical modulator of B cell function, leads to development of Sjögren's syndrome. 18624351 2008
Entrez Id: 9020
Gene Symbol: MAP3K14
MAP3K14 		0.200 Biomarker disease MGD Structure of thymic cysts in congenital lymph nodes-lacking mice. 17986312 2008
Entrez Id: 355
Gene Symbol: FAS
FAS 		0.200 Biomarker disease MGD Lymphocytic infiltration and goblet cell marker alteration in the conjunctiva of the MRL/MpJ-Fas(lpr) mouse model of Sjögren's syndrome. 17208228 2007
Entrez Id: 355
Gene Symbol: FAS
FAS 		0.200 Biomarker disease MGD Unexpected development of autoimmunity in BAFF-R-mutant MRL-lpr mice. 17073941 2007
Entrez Id: 1236
Gene Symbol: CCR7
CCR7 		0.200 Biomarker disease MGD CCR7-dependent cortex-to-medulla migration of positively selected thymocytes is essential for establishing central tolerance. 16473829 2006
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.200 Biomarker disease MGD Conditional ablation of MHC-II suggests an indirect role for MHC-II in regulatory CD4 T cell maintenance. 16709807 2006
Entrez Id: 3559
Gene Symbol: IL2RA
IL2RA 		0.200 Biomarker disease MGD Novel animal models for Sjögren's syndrome: expression and transfer of salivary gland dysfunction from regulatory T cell-deficient mice. 17207605 2006
Entrez Id: 9020
Gene Symbol: MAP3K14
MAP3K14 		0.200 Biomarker disease MGD Nematode infection in Alymphoplasia (aly) mice: worm species-dependent differential effect of defects of the gut-associated lymphatic tissue system. 16640660 2006
Entrez Id: 9020
Gene Symbol: MAP3K14
MAP3K14 		0.200 Biomarker disease MGD Impaired function of dendritic cells in alymphoplasia (aly/aly) mice for expansion of CD25+CD4+ regulatory T cells. 17060023 2006
Entrez Id: 3558
Gene Symbol: IL2
IL2 		0.200 Biomarker disease MGD Novel animal models for Sjögren's syndrome: expression and transfer of salivary gland dysfunction from regulatory T cell-deficient mice. 17207605 2006
Entrez Id: 3565
Gene Symbol: IL4
IL4 		0.200 Biomarker disease MGD Sjögren's syndrome in the NOD mouse model is an interleukin-4 time-dependent, antibody isotype-specific autoimmune disease. 16413168 2006
Entrez Id: 355
Gene Symbol: FAS
FAS 		0.200 Biomarker disease MGD Deficiency of P-selectin or P-selectin glycoprotein ligand-1 leads to accelerated development of glomerulonephritis and increased expression of CC chemokine ligand 2 in lupus-prone mice. 17142777 2006
Entrez Id: 326
Gene Symbol: AIRE
AIRE 		0.200 Biomarker disease MGD Development of autoimmunity against transcriptionally unrepressed target antigen in the thymus of Aire-deficient mice. 15699112 2005