Source: ALL
Variant Gene Risk Allele Score vda Association Type Original DB Sentence supporting the association PMID PMID Year
dbSNP: rs4291
rs4291
ACE
0.010 GeneticVariation BEFREE The study demonstrates that TT genotype of rs4291 or DD genotype of rs4646994 may be indicative of a higher risk of SS and a poorer prognosis in SS patients. 28336767

2017
dbSNP: rs3771863
rs3771863
TACR1 ; LOC105374811
0.010 GeneticVariation BEFREE Minor allele of the rs3771863 SNP from the TACR1 gene showed a significant association with a lower risk of sicca syndrome (pooled and adjusted OR 0.56, [95%CI 0.42-0.76], p=0.00022). 25786041

2015
dbSNP: rs530390117
rs530390117
FASLG
0.010 GeneticVariation BEFREE Direct sequencing revealed a heterozygous point mutation ( - 259T/C) in the FasL gene promoter region in one SS patient with EEG. 17966039

2007
dbSNP: rs1217691063
rs1217691063
MTHFR
0.010 GeneticVariation BEFREE We therefore investigated a possible role of the MTHFR C677T polymorphism in SS disease patients with stroke. 10583261

1999