Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 31
Gene Symbol: ACACA
ACACA 		0.300 Biomarker disease CTD_human Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. 26670611 2016
Entrez Id: 35
Gene Symbol: ACADS
ACADS 		0.300 Biomarker disease CTD_human [Change of short-chain acyl-CoA dehydrogenase in heart failure after myocardial infarction in rats and the intervention of aerobic exercise]. 30827304 2019
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.310 Biomarker disease BEFREE Furthermore, right ventricle-targeted therapies, aimed at mitigating the effects of functional right ventricular failure, include β-adrenoceptor (β-AR) blockers, angiotensin-converting enzyme (ACE) inhibitors, antioxidants, modulators of metabolism, and 5-hydroxytryptamine-2B (5-HT2B) receptor antagonists. 26583148 2015
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.310 Biomarker disease CTD_human Aldosterone synthase inhibition improves cardiovascular function and structure in rats with heart failure: a comparison with spironolactone. 18586661 2008
Entrez Id: 47
Gene Symbol: ACLY
ACLY 		0.300 Biomarker disease CTD_human Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. 26670611 2016
Entrez Id: 11095
Gene Symbol: ADAMTS8
ADAMTS8 		0.010 Biomarker disease BEFREE ADAMTS8 Promotes the Development of Pulmonary Arterial Hypertension and Right Ventricular Failure: A Possible Novel Therapeutic Target. 31556812 2019
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Biomarker disease CTD_human Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. 26670611 2016
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Therapeutic disease CTD_human Inhibition of G-protein-coupled Receptor Kinase 2 Prevents the Dysfunctional Cardiac Substrate Metabolism in Fatty Acid Synthase Transgenic Mice. 26670611 2016
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Biomarker disease CTD_human Effect of carvedilol on plasma adiponectin concentration in patients with chronic heart failure. 19367012 2009
Entrez Id: 9370
Gene Symbol: ADIPOQ
ADIPOQ 		0.300 Therapeutic disease CTD_human Effect of carvedilol on plasma adiponectin concentration in patients with chronic heart failure. 19367012 2009
Entrez Id: 152
Gene Symbol: ADRA2C
ADRA2C 		0.300 Biomarker disease CTD_human Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure. 12374873 2002
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1 		0.300 Biomarker disease CTD_human The control of cardiomyocyte apoptosis via the beta-adrenergic signaling pathways. 15816327 2005
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1 		0.300 Biomarker disease CTD_human Long-term treatment with angiotensin I-converting enzyme inhibitors attenuates the loss of cardiac beta-adrenoceptor responses in rats with chronic heart failure. 7586371 1995
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1 		0.300 Biomarker disease CTD_human Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure. 14502278 2003
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1 		0.300 Biomarker disease CTD_human Synergistic polymorphisms of beta1- and alpha2C-adrenergic receptors and the risk of congestive heart failure. 12374873 2002
Entrez Id: 153
Gene Symbol: ADRB1
ADRB1 		0.300 Biomarker disease CTD_human [Impact of Gly389Arg beta1-adrenoceptor polymorphism on the risk of chronic heart failure, the nature of its course, and on the efficiency of its treatment with carvedilol]. 21516734 2010
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3 		0.300 Biomarker disease CTD_human [Effect of beta3-adrenoreceptors agonist on beta3-adrenoreceptors expression and myocyte apoptosis in a rat model of heart failure]. 15009959 2004
Entrez Id: 155
Gene Symbol: ADRB3
ADRB3 		0.300 Biomarker disease CTD_human Effect of beta-blockers on beta3-adrenoceptor expression in chronic heart failure. 17440824 2007
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.310 Biomarker disease CTD_human Differential effects of captopril and enalapril on tissue renin-angiotensin systems in experimental heart failure. 1330361 1992
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.310 Biomarker disease BEFREE Effects of combined angiotensin II receptor antagonism and neprilysin inhibition in experimental pulmonary hypertension and right ventricular failure. 31307846 2019
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.310 Biomarker disease CTD_human Levosimendan improves cardiac function and survival in rats with angiotensin II-induced hypertensive heart failure. 20811386 2010
Entrez Id: 183
Gene Symbol: AGT
AGT 		0.310 Biomarker disease CTD_human [Pathophysiology of heart failure today]. 12025466 2002
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1 		0.310 Biomarker disease CTD_human Comparison of the cardioprotective effects of cardos and losartan in rats with experimental chronic cardiac insufficiency. 18214293 2007
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1 		0.310 AlteredExpression disease BEFREE Our findings indicate that the myocardium of rats with monocrotaline-induced right ventricular failure is deficient with activation of local RAS and therefore expresses blunted SFR, very similar to the depression of SFR observed in normal myocardium under inhibition of AT1 receptors. 29593122 2018
Entrez Id: 185
Gene Symbol: AGTR1
AGTR1 		0.310 Biomarker disease CTD_human Aldosterone synthase inhibition improves cardiovascular function and structure in rats with heart failure: a comparison with spironolactone. 18586661 2008