×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
GeneticVariation
group
CLINVAR
Familial paragangliomas: case report and literature review.
18753105
2009
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
Biomarker
group
BEFREE
All nine pediatric/adolescent GIST s and seven adult wild-type GIST s were negative for SDHB immunohistochemistry.
23174939
2013
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
[Intrapericardical paraganglioma associated with mutation in succinate dehydrogenase enzyme gene].
24939699
2015
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
A comprehensive next generation sequencing-based genetic testing strategy to improve diagnosis of inherited pheochromocytoma and paraganglioma.
23666964
2013
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
High frequency of SDHB germline mutations in patients with malignant catecholamine-producing paragangliomas: implications for genetic testing.
16912137
2006
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Novel germline mutations in the SDHB and SDHD genes in Japanese pheochromocytomas.
17308434
2007
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Mutation of SDHB is a cause of hypoxia-related high-altitude paraganglioma.
20592014
2010
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Pheochromocytoma and paraganglioma syndromes: genetics and management update.
24523625
2014
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
GeneticVariation
group
BEFREE
Succinate dehydrogenase-deficient gastrointestinal stromal tumors (SDH -deficient GISTs) are a unique class of GIST defined by negative immunohistochemical staining for succinate dehydrogenase B (SDHB).
23060355
2013
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Succinate Dehydrogenase (SDH)-Deficient Pancreatic Neuroendocrine Tumor Expands the SDH-Related Tumor Spectrum.
26259135
2015
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
GeneticVariation
group
BEFREE
The great majority of GIST s harbour mutually exclusive activating mutations in genes coding for the type III receptor tyrosine kinases KIT and PDGFRA; less commonly, GISTs have also been reported to display mutations elsewhere, including BRAF and NF1 and SDH -complex genes.
27943096
2017
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
GeneticVariation
group
CLINVAR
Screening of mutations in genes that predispose to hereditary paragangliomas and pheochromocytomas.
22517554
2012
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Pituitary adenoma with paraganglioma/pheochromocytoma (3PAs) and succinate dehydrogenase defects in humans and mice.
25695889
2015
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Genetic testing in pheochromocytoma or functional paraganglioma.
16314641
2005
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Missense mutations in the human SDHB gene increase protein degradation without altering intrinsic enzymatic function.
22835832
2012
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Phenotype of SDHB mutation carriers in the Netherlands.
25047027
2014
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
Biomarker
group
GENOMICS_ENGLAND
Advantages and pitfalls of an extended gene panel for investigating complex neurometabolic phenotypes.
27604308
2016
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
GeneticVariation
group
CLINVAR
Succinate dehydrogenase kidney cancer: an aggressive example of the Warburg effect in cancer.
23083876
2012
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
Biomarker
group
BEFREE
All GIST s from patients with Carney-Stratakis syndrome and Carney triad were negative for SDHB immunohistochemically.
20890271
2011
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
High prevalence of founder mutations of the succinate dehydrogenase genes in the Netherlands.
21348866
2012
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Malignant paraganglioma associated with succinate dehydrogenase subunit B in an 8-year-old child: the age of first screening?
19189136
2009
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma.
11404820
2001
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
Biomarker
group
GENOMICS_ENGLAND
Recessive germline SDHA and SDHB mutations causing leukodystrophy and isolated mitochondrial complex II deficiency.
22972948
2012
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
CausalMutation
group
CLINVAR
Clinical presentations, biochemical phenotypes, and genotype-phenotype correlations in patients with succinate dehydrogenase subunit B-associated pheochromocytomas and paragangliomas.
17200167
2007
×
Entrez Id:
6390
Gene Symbol:
SDHB
SDHB
0.800
Biomarker
group
BEFREE
Immunohistochemically, the GIST s are CD117, DOG-1 positive, SDHA negative (if SDHA mutated), SDHA positive (if SDHA intact) and SDHB negative.
27317811
2016