Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.210 GeneticVariation disease LHGDN Association between urokinase haplotypes and outcome from infection-associated acute lung injury. 17994220 2008
Entrez Id: 4486
Gene Symbol: MST1R
MST1R 		0.010 GeneticVariation disease LHGDN To examine the role of Mst1r in ALI in more detail, we compared the gene expression profiles of murine lung mRNA from control and Mst1r TK-/- mice at baseline and after 24 h of particulate Ni sulfate exposure. 16166746 2006
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.500 Biomarker disease CTD_human Protective effect of quercetin on acute lung injury in rats with sepsis and its influence on ICAM-1 and MIP-2 expression. 27525872 2016
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2 		0.500 Biomarker disease CTD_human Protective effect of quercetin on acute lung injury in rats with sepsis and its influence on ICAM-1 and MIP-2 expression. 27525872 2016
Entrez Id: 3383
Gene Symbol: ICAM1
ICAM1 		0.500 Biomarker disease CTD_human Intercellular adhesion molecule-1 (ICAM-1) is involved in neutrophil transmigration across endothelium during sepsis-induced acute lung injury and anti-ICAM-1 interventions may represent new strategy of pulmonary protection. 17973899 2007
Entrez Id: 7432
Gene Symbol: VIP
VIP 		0.500 Biomarker disease RGD The present study was conducted to investigate the effects of VIP on TLR2/4 mRNA expressions on acute lung injury of endotoxic shock induced by lipopolysaccharide (LPS) in rat. 20441697 2010
Entrez Id: 2920
Gene Symbol: CXCL2
CXCL2 		0.500 Biomarker disease RGD Delay of LPS-induced acute lung injury resolution by soluble immune complexes is neutrophil dependent. 19106808 2009
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.500 Biomarker disease RGD Decreased expression of peroxisome proliferator-activated receptor gamma in endotoxin-induced acute lung injury. 16083301 2006
Entrez Id: 1906
Gene Symbol: EDN1
EDN1 		0.300 Biomarker disease CTD_human Effects of endothelin receptor antagonism on acute lung injury induced by chlorine gas. 16625121 2006
Entrez Id: 3605
Gene Symbol: IL17A
IL17A 		0.300 Biomarker disease CTD_human IL-17A involves the ALI induced by LPS or PQ and promotes the pathological process by activating NF-κB P65 and recruiting neutrophils, which enlarges the cascade effect of inflammation and injures lung tissues. 28600744 2017
Entrez Id: 355
Gene Symbol: FAS
FAS 		0.300 Biomarker disease CTD_human [Effects of dexamethasone on apoptosis and expression of Fas/FasL system in lung tissues of ALI rats]. 11778176 2000
Entrez Id: 2052
Gene Symbol: EPHX1
EPHX1 		0.300 Biomarker disease CTD_human Naphthalene cytotoxicity in microsomal epoxide hydrolase deficient mice. 26840748 2016
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1 		0.300 Biomarker disease CTD_human Gene expression changes during the development of acute lung injury: role of transforming growth factor beta. 16100012 2005
Entrez Id: 356
Gene Symbol: FASLG
FASLG 		0.300 Biomarker disease CTD_human [Effects of dexamethasone on apoptosis and expression of Fas/FasL system in lung tissues of ALI rats]. 11778176 2000
Entrez Id: 7031
Gene Symbol: TFF1
TFF1 		0.300 Biomarker disease CTD_human Airway trefoil factor expression during naphthalene injury and repair. 19880587 2010
Entrez Id: 90
Gene Symbol: ACVR1
ACVR1 		0.300 Biomarker disease CTD_human This approach identified several candidate genes, including Acvr1, associated with increased susceptibility to acute lung injury in mice. 21297076 2011
Entrez Id: 4638
Gene Symbol: MYLK
MYLK 		0.300 Biomarker disease CTD_human The results suggest that MLCK has a crucial role in the pathogenesis of ALI. 19374788 2009
Entrez Id: 7032
Gene Symbol: TFF2
TFF2 		0.300 Biomarker disease CTD_human Airway trefoil factor expression during naphthalene injury and repair. 19880587 2010
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.210 Biomarker disease RGD Insulin reduces LPS-induced lethality and lung injury in rats. 22982561 2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.210 Biomarker disease RGD Regulatory effects of endogenous interleukin-1 receptor antagonist protein in immunoglobulin G immune complex-induced lung injury. 8613550 1996
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.210 Biomarker disease RGD In vivo effect of surfactant on inflammatory cytokines during endotoxin-induced lung injury in rodents. 21767135 2012
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.210 Biomarker disease RGD [Effects of hyperbaric oxygen on the acute lung injury induced by oleic acid in rats]. 20663306 2010
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.210 Biomarker disease RGD [Effect of inhalation of aerosolized unfractioned heparin on peri alveolar coagulability and inflammatory response in endotoxin induced acute lung injury rat model]. 21473829 2011
Entrez Id: 2152
Gene Symbol: F3
F3 		0.200 Biomarker disease RGD Airway tissue factor-dependent coagulation activity in response to sulfur mustard analog 2-chloroethyl ethyl sulfide. 21964405 2012
Entrez Id: 1991
Gene Symbol: ELANE
ELANE 		0.200 Biomarker disease RGD The present study was designed to elucidate the role of nitric oxide (NO), inducible NO synthase (iNOS), neutrophil elastase (NE) and other mediators in the ALI caused by PMA. 18283562 2008