×
Entrez Id: 3689
Gene Symbol: ITGB2
ITGB2
0.200
Biomarker
disease
RGD
Lung injury after deposition of IgA immune complexes. Requirements for CD18 and L-arginine.
1374449 1992
×
Entrez Id: 6372
Gene Symbol: CXCL6
CXCL6
0.200
Biomarker
disease
RGD
Chemokine expression during hepatic ischemia/reperfusion-induced lung injury in the rat. The role of epithelial neutrophil activating protein.
7814607 1995
×
Entrez Id: 2936
Gene Symbol: GSR
GSR
0.200
Biomarker
disease
RGD
Rapid neutrophil accumulation and protein oxidation in irradiated rat lungs.
7896613 1994
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.210
Biomarker
disease
RGD
Regulatory effects of endogenous interleukin-1 receptor antagonist protein in immunoglobulin G immune complex-induced lung injury.
8613550 1996
×
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
0.200
Biomarker
disease
RGD
Regulatory effects of endogenous interleukin-1 receptor antagonist protein in immunoglobulin G immune complex-induced lung injury.
8613550 1996
×
Entrez Id: 7432
Gene Symbol: VIP
VIP
0.500
Therapeutic
disease
CTD_human
Excitotoxicity in the lung: N-methyl-D-aspartate-induced, nitric oxide-dependent, pulmonary edema is attenuated by vasoactive intestinal peptide and by inhibitors of poly(ADP-ribose) polymerase.
8643465 1996
×
Entrez Id: 7498
Gene Symbol: XDH
XDH
0.200
Therapeutic
disease
RGD
Upregulation of xanthine oxidase by lipopolysaccharide, interleukin-1, and hypoxia. Role in acute lung injury.
9655743 1998
×
Entrez Id: 7077
Gene Symbol: TIMP2
TIMP2
0.200
ModifyingMutation
disease
RGD
Regulatory effects of endogenous protease inhibitors in acute lung inflammatory injury.
10092827 1999
×
Entrez Id: 6590
Gene Symbol: SLPI
SLPI
0.200
ModifyingMutation
disease
RGD
Regulatory effects of endogenous protease inhibitors in acute lung inflammatory injury.
10092827 1999
×
Entrez Id: 6351
Gene Symbol: CCL4
CCL4
0.200
Biomarker
disease
RGD
Role of CC chemokines (macrophage inflammatory protein-1 beta , monocyte chemoattractant protein-1, RANTES) in acute lung injury in rats.
10679105 2000
SERPINE1
0.200
Biomarker
disease
RGD
Priming for enhanced alveolar fibrin deposition after hemorrhagic shock: role of tumor necrosis factor.
10745022 2000
×
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.200
Therapeutic
disease
RGD
Topical hepatic hypothermia attenuates pulmonary injury after hepatic ischemia and reperfusion.
11129814 2000
×
Entrez Id: 355
Gene Symbol: FAS
FAS
0.300
Biomarker
disease
CTD_human
[Effects of dexamethasone on apoptosis and expression of Fas/FasL system in lung tissues of ALI rats].
11778176 2000
×
Entrez Id: 356
Gene Symbol: FASLG
FASLG
0.300
Biomarker
disease
CTD_human
[Effects of dexamethasone on apoptosis and expression of Fas/FasL system in lung tissues of ALI rats].
11778176 2000
×
Entrez Id: 3553
Gene Symbol: IL1B
IL1B
0.210
AlteredExpression
disease
LHGDN
Pulmonary edema fluid from patients with early lung injury stimulates fibroblast proliferation through IL-1 beta-induced IL-6 expression.
14764742 2004
×
Entrez Id: 1991
Gene Symbol: ELANE
ELANE
0.200
Therapeutic
disease
RGD
Beneficial effect of an inhibitor of leukocyte elastase (EPI-hNE-4) in presence of repeated lung injuries.
15257085 2004
×
Entrez Id: 3596
Gene Symbol: IL13
IL13
0.200
Biomarker
disease
RGD
To study the role of pro-inflammatory cytokines including tumor necrosis factor-alpha(TNF-alpha), interleukin-1beta(IL-1beta), IL-6, and anti-inflammatory cytokines including IL-4, IL-10, and IL-13 in acute lung injury (ALI).
15461830 2004
×
Entrez Id: 847
Gene Symbol: CAT
CAT
0.300
Therapeutic
disease
CTD_human
Effects of various antioxidants on endotoxin-induced lung injury and gene expression: mRNA expressions of MnSOD, interleukin-1beta and iNOS.
15612528 2004
×
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN
0.200
Biomarker
disease
RGD
(1)ALI is characterized by overwhelming expression of TNF-alpha mRNA, IL-1beta mRNA, while the expression of IL-1ra mRNA is much delayed than TNF-alpha mRNA and IL-1beta mRNA.
15970097 2005
×
Entrez Id: 5468
Gene Symbol: PPARG
PPARG
0.500
Biomarker
disease
RGD
Decreased expression of peroxisome proliferator-activated receptor gamma in endotoxin-induced acute lung injury .
16083301 2006
×
Entrez Id: 7040
Gene Symbol: TGFB1
TGFB1
0.300
Biomarker
disease
CTD_human
Gene expression changes during the development of acute lung injury: role of transforming growth factor beta.
16100012 2005
×
Entrez Id: 4486
Gene Symbol: MST1R
MST1R
0.010
GeneticVariation
disease
LHGDN
To examine the role of Mst1r in ALI in more detail, we compared the gene expression profiles of murine lung mRNA from control and Mst1r TK-/- mice at baseline and after 24 h of particulate Ni sulfate exposure.
16166746 2006
×
Entrez Id: 7295
Gene Symbol: TXN
TXN
0.300
Therapeutic
disease
CTD_human
Thioredoxin-1 suppresses lung injury and apoptosis induced by diesel exhaust particles (DEP) by scavenging reactive oxygen species and by inhibiting DEP-induced downregulation of Akt.
16298680 2005
×
Entrez Id: 1906
Gene Symbol: EDN1
EDN1
0.300
Biomarker
disease
CTD_human
Effects of endothelin receptor antagonism on acute lung injury induced by chlorine gas.
16625121 2006
×
Entrez Id: 1543
Gene Symbol: CYP1A1
CYP1A1
0.200
Biomarker
disease
RGD
Cooperation of the inducible nitric oxide synthase and cytochrome P450 1A1 in mediating lung inflammation and mutagenicity induced by diesel exhaust particles.
16882535 2006