Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.330 Biomarker disease BEFREE Thyroid Hormone Receptor-β Agonist GC-1 Inhibits Met-β-Catenin-Driven Hepatocellular Cancer. 28807594 2017
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.330 Biomarker disease BEFREE Tumor suppressor function of ezrin-radixin-moesin-binding phosphoprotein-50 through β-catenin/E-cadherin pathway in human hepatocellular cancer. 23483729 2013
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.330 Biomarker disease BEFREE γ-Catenin at adherens junctions: mechanism and biologic implications in hepatocellular cancer after β-catenin knockdown. 23555187 2013
Entrez Id: 1499
Gene Symbol: CTNNB1
CTNNB1 		0.330 GeneticVariation disease ORPHANET Childhood hepatoblastomas frequently carry a mutated degradation targeting box of the beta-catenin gene. 9927029 1999
Entrez Id: 4233
Gene Symbol: MET
MET 		0.300 SomaticCausalMutation disease ORPHANET Somatic mutations in the kinase domain of the Met/hepatocyte growth factor receptor gene in childhood hepatocellular carcinomas. 9927037 1999
Entrez Id: 174
Gene Symbol: AFP
AFP 		0.070 Biomarker disease BEFREE Hepatocellular cancer-derived alpha fetoprotein uptake reduces CD1 molecules on monocyte-derived dendritic cells. 30392891 2019
Entrez Id: 174
Gene Symbol: AFP
AFP 		0.070 GeneticVariation disease BEFREE By applying the approach to 286 hepatocellular tumour samples, they successfully uncover numerous driver aberration regions across the cancer genome, for example, chromosomes 4p and 5q, which harbour many known hepatocellular cancer related genes such as alpha-fetoprotein (AFP) and ectodermal-neural cortex (ENC1). 25014222 2014
Entrez Id: 174
Gene Symbol: AFP
AFP 		0.070 Biomarker disease BEFREE Alpha fetoprotein DNA prime and adenovirus boost immunization of two hepatocellular cancer patients. 24708667 2014
Entrez Id: 174
Gene Symbol: AFP
AFP 		0.070 Biomarker disease BEFREE AFP, PIVKAII, GP3, SCCA-1 and follisatin as surveillance biomarkers for hepatocellular cancer in non-alcoholic and alcoholic fatty liver disease. 18638391 2008
Entrez Id: 174
Gene Symbol: AFP
AFP 		0.070 AlteredExpression disease BEFREE Silencing alpha-fetoprotein expression induces growth arrest and apoptosis in human hepatocellular cancer cell. 18657899 2008
Entrez Id: 174
Gene Symbol: AFP
AFP 		0.070 Biomarker disease BEFREE Hierarchy of alpha fetoprotein (AFP)-specific T cell responses in subjects with AFP-positive hepatocellular cancer. 16785570 2006
Entrez Id: 174
Gene Symbol: AFP
AFP 		0.070 Biomarker disease BEFREE T-cell responses to HLA-A*0201 immunodominant peptides derived from alpha-fetoprotein in patients with hepatocellular cancer. 14676113 2003
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5 		0.040 Biomarker disease BEFREE The dual-targeting approach was used to deliver the theranostic sodium iodide symporter (NIS) gene to hepatocellular cancer. 30683895 2019
Entrez Id: 406906
Gene Symbol: MIR122
MIR122 		0.040 Biomarker disease BEFREE miRNA122a regulation of gene therapy vectors targeting hepatocellular cancer stem cells. 29805757 2018
Entrez Id: 406906
Gene Symbol: MIR122
MIR122 		0.040 AlteredExpression disease BEFREE The role of miR-122 in the dysregulation of glucose-6-phosphate dehydrogenase (G6PD) expression in hepatocellular cancer. 29904144 2018
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5 		0.040 Biomarker disease BEFREE Hypoxia-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated sodium iodide symporter gene delivery. 27458162 2016
Entrez Id: 406906
Gene Symbol: MIR122
MIR122 		0.040 Biomarker disease BEFREE Our findings suggest that enhanced glycolysis is associated with CD133 (+) stem-like characteristics and that metabolic reprogramming through miR-122 or PDK4 may represent a novel therapeutic approach for the treatment of hepatocellular cancer. 26506419 2015
Entrez Id: 406906
Gene Symbol: MIR122
MIR122 		0.040 AlteredExpression disease BEFREE Reciprocal regulation of microRNA-122 and c-Myc in hepatocellular cancer: role of E2F1 and transcription factor dimerization partner 2. 24038073 2014
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5 		0.040 Biomarker disease BEFREE Sodium iodide symporter (NIS)-mediated radiovirotherapy of hepatocellular cancer using a conditionally replicating adenovirus. 23038026 2013
Entrez Id: 6528
Gene Symbol: SLC5A5
SLC5A5 		0.040 Biomarker disease BEFREE Image-guided, tumor stroma-targeted 131I therapy of hepatocellular cancer after systemic mesenchymal stem cell-mediated NIS gene delivery. 21587211 2011
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.030 GeneticVariation disease BEFREE Majority of AFB1 associated hepatocellular cancer cases carry TP53 mutant DNA, which is an indicator of AFB1 exposure, as well as hepatocellular cancer risk. 30594067 2019
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.030 Biomarker disease BEFREE Preoperative Serum IL6, IL8, and TNF-<i>α</i> May Predict the Recurrence of Hepatocellular Cancer. 31781194 2019
Entrez Id: 7157
Gene Symbol: TP53
TP53 		0.030 Biomarker disease BEFREE Here we found that suppressing TIP60 inhibited p53 K120 acetylation and thus rescued apoptosis induced by glucose deprivation in hepatocellular cancer cells. 29174981 2018
Entrez Id: 3939
Gene Symbol: LDHA
LDHA 		0.030 Biomarker disease BEFREE The miR-383-LDHA axis regulates cell proliferation, invasion and glycolysis in hepatocellular cancer. 28293396 2017
Entrez Id: 7124
Gene Symbol: TNF
TNF 		0.030 Biomarker disease BEFREE Adenovirus encoding XAF-1 and TNF‑α in the same open reading frame efficiently inhibits hepatocellular cancer cells. 27121136 2016