Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		0.130 GeneticVariation disease BEFREE Variants at the PDGFRA locus have also shown genome-wide significant association with corneal astigmatism. 23401653 2013
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		0.130 GeneticVariation disease BEFREE Recently, the rs7677751 single nucleotide polymorphism (SNP) at the platelet-derived growth factor receptor alpha (PDGFRA) locus was found to be associated with corneal astigmatism in people of Asian ancestry. 23761726 2013
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		0.130 GeneticVariation disease BEFREE This highlights the potential role of variants in PDGFRA in the genetic etiology of corneal astigmatism across diverse Asian populations. 22144915 2011
Entrez Id: 5156
Gene Symbol: PDGFRA
PDGFRA 		0.130 GeneticVariation disease GWASDB Genome-wide meta-analysis of five Asian cohorts identifies PDGFRA as a susceptibility locus for corneal astigmatism. 22144915 2011
Entrez Id: 401237
Gene Symbol: CASC15
CASC15 		0.110 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 401237
Gene Symbol: CASC15
CASC15 		0.110 GeneticVariation disease BEFREE Single marker-based association tests for corneal astigmatism identified four genome-wide significant loci (P < 5 × 10<sup>-8</sup>) near the genes ZC3H11B (1q41), LINC00340 (6p22.3), HERC2/OCA2 (15q13.1) and NPLOC4/TSPAN10 (17q25.3). 30306274 2018
Entrez Id: 8924
Gene Symbol: HERC2
HERC2 		0.110 GeneticVariation disease BEFREE Single marker-based association tests for corneal astigmatism identified four genome-wide significant loci (P < 5 × 10<sup>-8</sup>) near the genes ZC3H11B (1q41), LINC00340 (6p22.3), HERC2/OCA2 (15q13.1) and NPLOC4/TSPAN10 (17q25.3). 30306274 2018
Entrez Id: 55666
Gene Symbol: NPLOC4
NPLOC4 		0.110 GeneticVariation disease BEFREE Single marker-based association tests for corneal astigmatism identified four genome-wide significant loci (P < 5 × 10<sup>-8</sup>) near the genes ZC3H11B (1q41), LINC00340 (6p22.3), HERC2/OCA2 (15q13.1) and NPLOC4/TSPAN10 (17q25.3). 30306274 2018
Entrez Id: 55666
Gene Symbol: NPLOC4
NPLOC4 		0.110 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 83882
Gene Symbol: TSPAN10
TSPAN10 		0.110 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 8924
Gene Symbol: HERC2
HERC2 		0.110 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 83882
Gene Symbol: TSPAN10
TSPAN10 		0.110 GeneticVariation disease BEFREE Single marker-based association tests for corneal astigmatism identified four genome-wide significant loci (P < 5 × 10<sup>-8</sup>) near the genes ZC3H11B (1q41), LINC00340 (6p22.3), HERC2/OCA2 (15q13.1) and NPLOC4/TSPAN10 (17q25.3). 30306274 2018
Entrez Id: 23348
Gene Symbol: DOCK9
DOCK9 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 114793
Gene Symbol: FMNL2
FMNL2 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 2313
Gene Symbol: FLI1
FLI1 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 23389
Gene Symbol: MED13L
MED13L 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 11095
Gene Symbol: ADAMTS8
ADAMTS8 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 84727
Gene Symbol: SPSB2
SPSB2 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 7410
Gene Symbol: VAV2
VAV2 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 10233
Gene Symbol: LRRC23
LRRC23 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 4088
Gene Symbol: SMAD3
SMAD3 		0.100 GeneticVariation disease GWASCAT Genome-wide association studies for corneal and refractive astigmatism in UK Biobank demonstrate a shared role for myopia susceptibility loci. 30306274 2018
Entrez Id: 25806
Gene Symbol: VAX2
VAX2 		0.100 GeneticVariation disease GWASDB Identification of a candidate gene for astigmatism. 23322567 2013
Entrez Id: 1767
Gene Symbol: DNAH5
DNAH5 		0.100 GeneticVariation disease GWASDB Identification of a candidate gene for astigmatism. 23322567 2013
Entrez Id: 105369723
Gene Symbol: LINC02422
LINC02422 		0.100 GeneticVariation disease GWASDB Interrogation of the platelet-derived growth factor receptor alpha locus and corneal astigmatism in Australians of Northern European ancestry: results of a genome-wide association study. 23761726 2013
Entrez Id: 5308
Gene Symbol: PITX2
PITX2 		0.100 Biomarker disease HPO