Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.510 Biomarker disease MGD
Entrez Id: 50506
Gene Symbol: DUOX2
DUOX2 		0.500 Biomarker disease MGD
Entrez Id: 7173
Gene Symbol: TPO
TPO 		0.500 Biomarker disease MGD
Entrez Id: 7201
Gene Symbol: TRHR
TRHR 		0.200 Biomarker disease MGD
Entrez Id: 7849
Gene Symbol: PAX8
PAX8 		0.200 Biomarker disease MGD
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2 		0.200 Biomarker disease MGD
Entrez Id: 2304
Gene Symbol: FOXE1
FOXE1 		0.200 Biomarker disease MGD
Entrez Id: 7038
Gene Symbol: TG
TG 		0.200 Biomarker disease MGD
Entrez Id: 7200
Gene Symbol: TRH
TRH 		0.010 Biomarker disease BEFREE Other causes of cretinism include failure of the thyroid gland to respond to TSH and lack of pituitary TSH (or hypothalamic TRH). 782770 1976
Entrez Id: 3479
Gene Symbol: IGF1
IGF1 		0.200 Biomarker disease RGD The effects of thyroid hormone on insulin-like growth factor (IGF) and IGF-binding protein (IGFBP) expression in the neonatal rat: prolonged high expression of IGFBP-2 in methimazole-induced congenital hypothyroidism. 1718729 1991
Entrez Id: 632
Gene Symbol: BGLAP
BGLAP 		0.200 Biomarker disease RGD Studies on gene expression in calvaria and serum levels of insulin-like growth factor-I and bone Gla protein in the methimazole-induced congenital hypothyroid rat. 7920889 1993
Entrez Id: 3625
Gene Symbol: INHBB
INHBB 		0.200 Biomarker disease RGD Developmental expression of testis messenger ribonucleic acids in the rat following propylthiouracil-induced neonatal hypothyroidism. 7819453 1994
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.020 GeneticVariation disease BEFREE Our data suggest that in iodine-deficient areas, the APOE epsilon4 allele is a genetic risk factor for FIDD. 10889546 2000
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.510 Biomarker disease CTD_human The W546X mutation of the thyrotropin receptor gene: potential major contributor to thyroid dysfunction in a Caucasian population. 12629076 2003
Entrez Id: 7173
Gene Symbol: TPO
TPO 		0.500 Biomarker disease CTD_human Congenital hypothyroidism with goiter in toy fox terriers. 12564727 2003
Entrez Id: 7173
Gene Symbol: TPO
TPO 		0.500 Biomarker disease CTD_human Thyroperoxidase gene mutations in congenital goitrous hypothyroidism with total and partial iodide organification defect. 14751036 2003
Entrez Id: 7253
Gene Symbol: TSHR
TSHR 		0.510 Biomarker disease BEFREE In conclusion, our association results suggest that TSHR gene is not a susceptibility gene for FIDD in the iodine-deficient areas of China. 15911145 2005
Entrez Id: 7173
Gene Symbol: TPO
TPO 		0.500 Biomarker disease CTD_human Total iodide organification defect: clinical and molecular characterization of an Italian family. 16187919 2005
Entrez Id: 50506
Gene Symbol: DUOX2
DUOX2 		0.500 Biomarker disease CTD_human Persistent mild hypothyroidism associated with novel sequence variants of the DUOX2 gene in two siblings. 16134168 2005
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.020 Biomarker disease BEFREE Our previous study demonstrated that apolipoprotein E (ApoE) was a genetic risk factor for FIDD in the local area. 15739386 2005
Entrez Id: 1734
Gene Symbol: DIO2
DIO2 		0.010 Biomarker disease BEFREE In the previous study, we have proposed that DIO2 may protect against FIDD in the iodine-deficient areas of China. 15911145 2005
Entrez Id: 50506
Gene Symbol: DUOX2
DUOX2 		0.500 Biomarker disease CTD_human Three mutations (p.Q36H, p.G418fsX482, and g.IVS19-2A>C) in the dual oxidase 2 gene responsible for congenital goiter and iodide organification defect. 16322276 2006
Entrez Id: 7173
Gene Symbol: TPO
TPO 		0.500 Biomarker disease CTD_human Clinical and genetic characteristics of congenital hypothyroidism due to mutations in the thyroid peroxidase (TPO) gene in Israelis. 17381485 2007
Entrez Id: 4741
Gene Symbol: NEFM
NEFM 		0.200 Biomarker disease RGD Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. 18845185 2008
Entrez Id: 4744
Gene Symbol: NEFH
NEFH 		0.200 Biomarker disease RGD Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. 18845185 2008