Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
0.510 Biomarker disease MGD
Entrez Id: 50506
Gene Symbol: DUOX2
DUOX2
0.500 Biomarker disease MGD
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.500 Biomarker disease MGD
Entrez Id: 7201
Gene Symbol: TRHR
TRHR
0.200 Biomarker disease MGD
Entrez Id: 7849
Gene Symbol: PAX8
PAX8
0.200 Biomarker disease MGD
Entrez Id: 860
Gene Symbol: RUNX2
RUNX2
0.200 Biomarker disease MGD
Entrez Id: 2304
Gene Symbol: FOXE1
FOXE1
0.200 Biomarker disease MGD
Entrez Id: 7038
Gene Symbol: TG
TG
0.200 Biomarker disease MGD
Entrez Id: 2688
Gene Symbol: GH1
GH1
0.200 Therapeutic disease RGD Changes in growth hormone (GH), GH receptor, and GH signal transduction in hippocampus of congenital hypothyroid rats. 21162131 2011
Entrez Id: 2690
Gene Symbol: GHR
GHR
0.200 Therapeutic disease RGD Changes in growth hormone (GH), GH receptor, and GH signal transduction in hippocampus of congenital hypothyroid rats. 21162131 2011
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.500 Biomarker disease CTD_human Clinical and genetic characteristics of congenital hypothyroidism due to mutations in the thyroid peroxidase (TPO) gene in Israelis. 17381485 2007
Entrez Id: 2539
Gene Symbol: G6PD
G6PD
0.200 Biomarker disease RGD Congenital hypothyroidism alters the oxidative status, enzyme activities and morphological parameters in the hippocampus of developing rats. 23693027 2013
Entrez Id: 4741
Gene Symbol: NEFM
NEFM
0.200 Biomarker disease RGD Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. 18845185 2008
Entrez Id: 4744
Gene Symbol: NEFH
NEFH
0.200 Biomarker disease RGD Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. 18845185 2008
Entrez Id: 4747
Gene Symbol: NEFL
NEFL
0.200 Biomarker disease RGD Congenital hypothyroidism is associated with intermediate filament misregulation, glutamate transporters down-regulation and MAPK activation in developing rat brain. 18845185 2008
Entrez Id: 7173
Gene Symbol: TPO
TPO
0.500 Biomarker disease CTD_human Congenital hypothyroidism with goiter in toy fox terriers. 12564727 2003
Entrez Id: 3625
Gene Symbol: INHBB
INHBB
0.200 Biomarker disease RGD Developmental expression of testis messenger ribonucleic acids in the rat following propylthiouracil-induced neonatal hypothyroidism. 7819453 1994
Entrez Id: 1958
Gene Symbol: EGR1
EGR1
0.200 Biomarker disease RGD Developmentally-induced hypothyroidism alters the expression of Egr-1 and Arc genes and the sensitivity to cannabinoid agonists in the hippocampus. Possible implications for memory and learning. 23079472 2013
Entrez Id: 10092
Gene Symbol: ARPC5
ARPC5
0.200 Biomarker disease RGD Effects of hypothyroidism on expression of CRMP2B and ARPC5 during development of the rat frontal cortex. 23459330 2013
Entrez Id: 10891
Gene Symbol: PPARGC1A
PPARGC1A
0.200 Biomarker disease RGD Evidence of a bigenomic regulation of mitochondrial gene expression by thyroid hormone during rat brain development. 20515651 2010
Entrez Id: 7253
Gene Symbol: TSHR
TSHR
0.510 Biomarker disease BEFREE In conclusion, our association results suggest that TSHR gene is not a susceptibility gene for FIDD in the iodine-deficient areas of China. 15911145 2005
Entrez Id: 1734
Gene Symbol: DIO2
DIO2
0.010 Biomarker disease BEFREE In the previous study, we have proposed that DIO2 may protect against FIDD in the iodine-deficient areas of China. 15911145 2005
Entrez Id: 4804
Gene Symbol: NGFR
NGFR
0.200 Therapeutic disease RGD Iodine plus n-3 fatty acid supplementation augments rescue of postnatal neuronal abnormalities in iodine-deficient rat cerebellum. 23312094 2013
Entrez Id: 3547
Gene Symbol: IGSF1
IGSF1
0.300 Biomarker disease CTD_human Loss-of-function mutations in IGSF1 cause an X-linked syndrome of central hypothyroidism and testicular enlargement. 23143598 2012
Entrez Id: 7200
Gene Symbol: TRH
TRH
0.010 Biomarker disease BEFREE Other causes of cretinism include failure of the thyroid gland to respond to TSH and lack of pituitary TSH (or hypothalamic TRH). 782770 1976