Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		0.300 Biomarker disease CTD_human A novel mutation in the PSEN2 gene (T430M) associated with variable expression in a family with early-onset Alzheimer disease. 12925374 2003
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease. 28448946 2017
Entrez Id: 3635
Gene Symbol: INPP5D
INPP5D 		0.300 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Biomarker disease CTD_human Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease. 11144356 2000
Entrez Id: 100126333
Gene Symbol: MIR708
MIR708 		0.300 Biomarker disease CTD_human MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease. 25992776 2015
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human pH-Dependent Cu(II) coordination to amyloid-β peptide: impact of sequence alterations, including the H6R and D7N familial mutations. 21980910 2011
Entrez Id: 51741
Gene Symbol: WWOX
WWOX 		0.300 Biomarker disease CTD_human Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. 30820047 2019
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Oxidation of cholesterol by amyloid precursor protein and beta-amyloid peptide. 15591071 2005
Entrez Id: 2
Gene Symbol: A2M
A2M 		0.300 Biomarker disease CTD_human Alpha-2 macroglobulin is genetically associated with Alzheimer disease. 9697696 1998
Entrez Id: 100616367
Gene Symbol: MIR4467
MIR4467 		0.300 Biomarker disease CTD_human MicroRNA Profiling of CSF Reveals Potential Biomarkers to Detect Alzheimer`s Disease. 25992776 2015
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease. 16651627 2006
Entrez Id: 51338
Gene Symbol: MS4A4A
MS4A4A 		0.300 Biomarker disease CTD_human Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. 21460841 2011
Entrez Id: 1965
Gene Symbol: EIF2S1
EIF2S1 		0.300 Biomarker disease CTD_human Minocycline attenuates neuronal cell death and improves cognitive impairment in Alzheimer's disease models. 17406652 2007
Entrez Id: 7447
Gene Symbol: VSNL1
VSNL1 		0.300 Biomarker disease CTD_human VSNL1 Co-Expression Networks in Aging Include Calcium Signaling, Synaptic Plasticity, and Alzheimer's Disease Pathways. 25806004 2015
Entrez Id: 7018
Gene Symbol: TF
TF 		0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007
Entrez Id: 54209
Gene Symbol: TREM2
TREM2 		0.300 Biomarker disease CTD_human Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. 28714976 2017
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. 1671712 1991
Entrez Id: 23607
Gene Symbol: CD2AP
CD2AP 		0.300 Biomarker disease CTD_human Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. 21460841 2011
Entrez Id: 341
Gene Symbol: APOC1
APOC1 		0.300 Biomarker disease CTD_human Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses. 29107063 2018
Entrez Id: 10452
Gene Symbol: TOMM40
TOMM40 		0.300 Biomarker disease CTD_human Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses. 29107063 2018
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker disease CTD_human Generation of Abeta38 and Abeta42 is independently and differentially affected by familial Alzheimer disease-associated presenilin mutations and gamma-secretase modulation. 17962197 2008
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		0.300 Biomarker disease CTD_human Beta-amyloid mediated nitration of manganese superoxide dismutase: implication for oxidative stress in a APPNLH/NLH X PS-1P264L/P264L double knock-in mouse model of Alzheimer's disease. 16651627 2006
Entrez Id: 4137
Gene Symbol: MAPT
MAPT 		0.300 Biomarker disease CTD_human Identification of the key molecules involved in chronic copper exposure-aggravated memory impairment in transgenic mice of Alzheimer's disease using proteomic analysis. 25352456 2015
Entrez Id: 3481
Gene Symbol: IGF2
IGF2 		0.300 Biomarker disease CTD_human Impaired insulin and insulin-like growth factor expression and signaling mechanisms in Alzheimer's disease--is this type 3 diabetes? 15750215 2005
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		0.300 Biomarker disease CTD_human Systematic meta-analyses of Alzheimer disease genetic association studies: the AlzGene database. 17192785 2007