Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.300 Biomarker disease CTD_human
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Segregation of a missense mutation in the amyloid precursor protein gene with familial Alzheimer's disease. 1671712 1991
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Mis-sense mutation Val----Ile in exon 17 of amyloid precursor protein gene in Japanese familial Alzheimer's disease. 1678058 1991
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Vitamin E protects nerve cells from amyloid beta protein toxicity. 1497677 1992
Entrez Id: 2147
Gene Symbol: F2
F2 		0.300 Biomarker disease CTD_human Non-age related differences in thrombin responses by platelets from male patients with advanced Alzheimer's disease. 8333868 1993
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Gene dose of apolipoprotein E type 4 allele and the risk of Alzheimer's disease in late onset families. 8346443 1993
Entrez Id: 4129
Gene Symbol: MAOB
MAOB 		0.300 Biomarker disease CTD_human Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography. 7816197 1994
Entrez Id: 1392
Gene Symbol: CRH
CRH 		0.300 Therapeutic disease CTD_human Displacement of corticotropin releasing factor from its binding protein as a possible treatment for Alzheimer's disease. 7477348 1995
Entrez Id: 1565
Gene Symbol: CYP2D6
CYP2D6 		0.300 Biomarker disease CTD_human The CYP2D6B allele is associated with a milder synaptic pathology in Alzheimer's disease. 7574463 1995
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker disease CTD_human Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease. 7596406 1995
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		0.300 Biomarker disease CTD_human The presenilin 2 mutation (N141I) linked to familial Alzheimer disease (Volga German families) increases the secretion of amyloid beta protein ending at the 42nd (or 43rd) residue. 9050898 1997
Entrez Id: 2
Gene Symbol: A2M
A2M 		0.300 Biomarker disease CTD_human Alpha-2 macroglobulin is genetically associated with Alzheimer disease. 9697696 1998
Entrez Id: 3630
Gene Symbol: INS
INS 		0.300 Biomarker disease CTD_human Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. 9443474 1998
Entrez Id: 2
Gene Symbol: A2M
A2M 		0.300 Biomarker disease CTD_human Genetic association of an alpha2-macroglobulin (Val1000lle) polymorphism and Alzheimer's disease. 9811940 1998
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.300 Biomarker disease CTD_human Variation in DCP1, encoding ACE, is associated with susceptibility to Alzheimer disease. 9916793 1999
Entrez Id: 4846
Gene Symbol: NOS3
NOS3 		0.300 Biomarker disease CTD_human Association between Alzheimer's disease and the NOS3 gene. 10514107 1999
Entrez Id: 1200
Gene Symbol: TPP1
TPP1 		0.300 Biomarker disease CTD_human Increased brain lysosomal pepstatin-insensitive proteinase activity in patients with neurodegenerative diseases. 10320038 1999
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.300 Biomarker disease CTD_human Angiotensin-converting enzyme genotype is associated with Alzheimer disease in the Japanese population. 10643899 1999
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Biomarker disease CTD_human Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease. 11144356 2000
Entrez Id: 4852
Gene Symbol: NPY
NPY 		0.300 Biomarker disease CTD_human Neuropeptide Y, peptide YY and aluminum in Alzheimer's disease: is there an etiological relationship? 11709213 2001
Entrez Id: 801
Gene Symbol: CALM1
CALM1 		0.300 Biomarker disease CTD_human Immunostaining of calmodulin and aluminium in Alzheimer's disease-affected brains. 11470324 2001
Entrez Id: 5697
Gene Symbol: PYY
PYY 		0.300 Biomarker disease CTD_human Neuropeptide Y, peptide YY and aluminum in Alzheimer's disease: is there an etiological relationship? 11709213 2001
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Metalloenzyme-like activity of Alzheimer's disease beta-amyloid. Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H(2)O(2). 12192006 2002
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		0.300 Biomarker disease CTD_human A novel mutation in the PSEN2 gene (T430M) associated with variable expression in a family with early-onset Alzheimer disease. 12925374 2003
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Impaired modulation of GABAergic transmission by muscarinic receptors in a mouse transgenic model of Alzheimer's disease. 12746438 2003