Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 5328
Gene Symbol: PLAU
PLAU 		0.300 Biomarker disease CTD_human
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human "How and when environmental agents and dietary factors affect the course of Alzheimer's disease: the ""LEARn"" model (latent early-life associated regulation) may explain the triggering of AD." 17430250 2007
Entrez Id: 5664
Gene Symbol: PSEN2
PSEN2 		0.300 Biomarker disease CTD_human A novel mutation in the PSEN2 gene (T430M) associated with variable expression in a family with early-onset Alzheimer disease. 12925374 2003
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker disease CTD_human A presenilin-1 mutation renders neurons vulnerable to isoflurane toxicity. 18227305 2008
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis. 19286555 2009
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Aβ40 oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease. 21209907 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Abeta peptides as one of the crucial volume transmission signals in the trophic units and their interactions with homocysteine. Physiological implications and relevance for Alzheimer's disease. 16969627 2007
Entrez Id: 23237
Gene Symbol: ARC
ARC 		0.300 Biomarker disease CTD_human Activity-regulated cytoskeleton-associated protein in rodent brain is down-regulated by high fat diet in vivo and by 27-hydroxycholesterol in vitro. 18503570 2009
Entrez Id: 5468
Gene Symbol: PPARG
PPARG 		0.300 Biomarker disease CTD_human Agonists of peroxisome proliferator-activated receptor-gamma attenuate the Abeta-mediated impairment of LTP in the hippocampus in vitro. 15993441 2005
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Agonists of peroxisome proliferator-activated receptor-gamma attenuate the Abeta-mediated impairment of LTP in the hippocampus in vitro. 15993441 2005
Entrez Id: 2
Gene Symbol: A2M
A2M 		0.300 Biomarker disease CTD_human Alpha-2 macroglobulin is genetically associated with Alzheimer disease. 9697696 1998
Entrez Id: 1139
Gene Symbol: CHRNA7
CHRNA7 		0.300 Biomarker disease CTD_human Alpha7 nicotinic receptor up-regulation in cholinergic basal forebrain neurons in Alzheimer disease. 18071042 2007
Entrez Id: 55676
Gene Symbol: SLC30A6
SLC30A6 		0.300 Biomarker disease CTD_human Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain. 16580781 2006
Entrez Id: 7782
Gene Symbol: SLC30A4
SLC30A4 		0.300 Biomarker disease CTD_human Altered expression of zinc transporters-4 and -6 in mild cognitive impairment, early and late Alzheimer's disease brain. 16580781 2006
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.300 Biomarker disease CTD_human Alzheimer disease risk and genetic variation in ACE: a meta-analysis. 14872014 2004
Entrez Id: 1718
Gene Symbol: DHCR24
DHCR24 		0.300 Biomarker disease CTD_human Alzheimer's disease: brain desmosterol levels. 23042211 2013
Entrez Id: 10857
Gene Symbol: PGRMC1
PGRMC1 		0.300 Biomarker disease CTD_human Alzheimer's therapeutics targeting amyloid beta 1-42 oligomers II: Sigma-2/PGRMC1 receptors mediate Abeta 42 oligomer binding and synaptotoxicity. 25390692 2014
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1 		0.300 Biomarker disease CTD_human Amyloid precursor proteins inhibit heme oxygenase activity and augment neurotoxicity in Alzheimer's disease. 11144356 2000
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human Amyloid-beta peptide binds with heme to form a peroxidase: relationship to the cytopathologies of Alzheimer's disease. 16492752 2006
Entrez Id: 1636
Gene Symbol: ACE
ACE 		0.300 Biomarker disease CTD_human Angiotensin-converting enzyme genotype is associated with Alzheimer disease in the Japanese population. 10643899 1999
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human APP expression, distribution and accumulation are altered by aluminum in a rodent model for Alzheimer's disease. 19818510 2009
Entrez Id: 351
Gene Symbol: APP
APP 		0.300 Biomarker disease CTD_human APP/PS1 transgenic mice treated with aluminum: an update of Alzheimer's disease model. 22507317 2012
Entrez Id: 5663
Gene Symbol: PSEN1
PSEN1 		0.300 Biomarker disease CTD_human APP/PS1 transgenic mice treated with aluminum: an update of Alzheimer's disease model. 22507317 2012
Entrez Id: 590
Gene Symbol: BCHE
BCHE 		0.300 Biomarker disease CTD_human Association analysis between K and -116A variants of butyrylcholinesterase and Alzheimer's disease in a Brazilian population. 23022600 2013
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.300 Biomarker disease CTD_human Association Analysis of Polymorphisms in TOMM40, CR1, PVRL2, SORL1, PICALM, and 14q32.13 Regions in Colombian Alzheimer Disease Patients. 27023435 2017