Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 7263
Gene Symbol: TST
TST
0.060 GeneticVariation disease BEFREE Three hundred and thirty-two strains isolated from ten provinces between June 1999 and January 2002 were characterized by staphylococcal enterotoxin genes, toxic shock syndrome toxin 1 (tst) gene, and exfoliative toxin genes. 16968298 2006
Entrez Id: 7263
Gene Symbol: TST
TST
0.060 GeneticVariation disease BEFREE Antibiotic susceptibility, biofilm formation, Staphylococcal protein A (spa) typing, SCCmec typing, and PCR-based assays were used to detect mecA, mecC, vanA, Panton-Valentine Leukocidin toxin (PVL), and toxic shock syndrome toxin-1 (tst) genes. 28784993 2017
Entrez Id: 7263
Gene Symbol: TST
TST
0.060 GeneticVariation disease BEFREE The isolates did not display any consistent virulence gene pattern, and 35 % of the isolates carried at least one of the Panton-Valentine leukocidin (lukFS-PV), exfoliative toxin (eta) or toxic shock syndrome (tst) genes. 28005521 2017
Entrez Id: 7263
Gene Symbol: TST
TST
0.060 GeneticVariation disease BEFREE Important characteristics, e.g., carriage of the enterotoxin A (sea) and toxic shock syndrome toxin (tst) genes and production of urease, are described. 15528709 2004
Entrez Id: 3586
Gene Symbol: IL10
IL10
0.030 GeneticVariation disease BEFREE The third objective was to assess IL-10 responses to endotoxin and toxic shock syndrome toxin (TSST) from leukocytes of smokers and non-smokers in relation to the IL-10 (G-1082A) polymorphism. 15325406 2004
Entrez Id: 10479
Gene Symbol: SLC9A6
SLC9A6
0.030 GeneticVariation disease BEFREE Staphylococcal enterotoxin A and toxic shock syndrome toxin-1 were prevalent among the adult MRSA isolates but not among the pediatric MRSA isolates. 17978805 2007
Entrez Id: 56477
Gene Symbol: CCL28
CCL28
0.010 GeneticVariation disease BEFREE Routine typing of meticillin-resistant Staphylococcus aureus (MRSA) was initiated in Austria 2005 and was performed by sequence analysis of the variable X region of protein A gene (spa), characterisation of the mec gene (SCCmec) and testing for Panton-Valentine leukocidin (PVL), enterotoxins, toxic shock syndrome toxin and the epidermolytic toxin genes. 18022286 2007
Entrez Id: 28619
Gene Symbol: TRBV3-1
TRBV3-1
0.010 GeneticVariation disease BEFREE We aimed to determine whether TCRBV3S1 allele 2 could be involved in a staphylococcal toxic shock hypothesis for uSUDI. 20362046 2010
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.010 GeneticVariation disease BEFREE We propose that the onset mechanism involved an increase in blood VEGF due to TSS, which induced RS3PE syndrome. 29653519 2018
Entrez Id: 28559
Gene Symbol: TRBV28
TRBV28
0.010 GeneticVariation disease BEFREE We aimed to determine whether TCRBV3S1 allele 2 could be involved in a staphylococcal toxic shock hypothesis for uSUDI. 20362046 2010
Entrez Id: 100526790
Gene Symbol: TST1
TST1
0.010 GeneticVariation disease BEFREE In this study, 28 bacteriocinogenic Staphylococcus strains isolated from goat and sheep milk were subjected to the PCR detection of enterotoxin genes (sea-see), enterotoxin-like toxin Q gene (selq), toxic shock syndrome toxin gene (tst1), and antibiotic resistance genes. 29355699 2018
Entrez Id: 3105
Gene Symbol: HLA-A
HLA-A
0.010 GeneticVariation disease BEFREE The study confirmed the previously observed lack of association of TSS with HLA-A and B locus antigens. 3928541 1985
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.540 Biomarker disease CTD_human Akt Cys-310-targeted inhibition by hydroxylated benzene derivatives is tightly linked to their immunosuppressive effects. 20054000 2010
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.540 Biomarker disease RGD [The effect of transmembrane- and secreted-tumor necrosis factor-alpha on shock liver]. 12622907 2002
Entrez Id: 7124
Gene Symbol: TNF
TNF
0.540 Biomarker disease BEFREE Using a matrigel invasion assay, we showed that TSS significantly attenuated invasive rates in TNF-α-stimulated LNCaP prostate carcinoma cells. 25168152 2014
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.500 Biomarker disease RGD Effect of nitric oxide synthase (NOS) inhibition on macro- and microcirculation in a model of rat endotoxic shock. 16601845 2006
Entrez Id: 4843
Gene Symbol: NOS2
NOS2
0.500 Biomarker disease CTD_human Expression of inducible nitric oxide synthase in failing and non-failing human heart. 8745224 1996
Entrez Id: 358
Gene Symbol: AQP1
AQP1
0.300 Biomarker disease CTD_human Induced expression and functional effects of aquaporin-1 in human leukocytes in sepsis. 24028651 2013
Entrez Id: 728
Gene Symbol: C5AR1
C5AR1
0.300 Biomarker disease CTD_human Disruption of the C5a receptor gene increases resistance to acute Gram-negative bacteremia and endotoxic shock: opposing roles of C3a and C5a. 18063050 2008
Entrez Id: 2638
Gene Symbol: GC
GC
0.300 Biomarker disease CTD_human Comparison of rocket and crossed immuno-electrophoresis assays for determination of the level of actin complexing of Gc globulin. 17852808 2007
Entrez Id: 3122
Gene Symbol: HLA-DRA
HLA-DRA
0.300 Biomarker disease CTD_human Human leucocyte antigen (HLA-DR) gene expression is reduced in sepsis and correlates with impaired TNFα response: A diagnostic tool for immunosuppression? 28771573 2017
Entrez Id: 4158
Gene Symbol: MC2R
MC2R
0.200 Biomarker disease RGD Metallothionein and zinc metabolism in endotoxin shock rats. 2822467 1987
Entrez Id: 6402
Gene Symbol: SELL
SELL
0.200 Biomarker disease RGD GYY4137, a novel hydrogen sulfide-releasing molecule, protects against endotoxic shock in the rat. 19375498 2009
Entrez Id: 4282
Gene Symbol: MIF
MIF
0.200 Biomarker disease RGD [Role of macrophage migration inhibitory factor in septic shock-induced cardiovascular dysfunction: experiment with rats]. 17565848 2007
Entrez Id: 3162
Gene Symbol: HMOX1
HMOX1
0.200 Biomarker disease RGD Protective effects of hemin pretreatment combined with ulinastatin on septic shock in rats. 18208666 2008