Source: CURATED ×
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses. 29107063 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Genome-Wide Association and Mechanistic Studies Indicate That Immune Response Contributes to Alzheimer's Disease Development. 30319691 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human High performance plasma amyloid-β biomarkers for Alzheimer's disease. 29420472 2018
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Quantitative Genetics Validates Previous Genetic Variants and Identifies Novel Genetic Players Influencing Alzheimer's Disease Cerebrospinal Fluid Biomarkers. 30320580 2018
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Association Analysis of Polymorphisms in TOMM40, CR1, PVRL2, SORL1, PICALM, and 14q32.13 Regions in Colombian Alzheimer Disease Patients. 27023435 2017
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Oral administration of methysticin improves cognitive deficits in a mouse model of Alzheimer's disease. 28448946 2017
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human The BET-Bromodomain Inhibitor JQ1 Reduces Inflammation and Tau Phosphorylation at Ser396 in the Brain of the 3xTg Model of Alzheimer's Disease. 27117003 2016
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Protective Effect of Notoginsenoside R1 on an APP/PS1 Mouse Model of Alzheimer's Disease by Up-Regulating Insulin Degrading Enzyme and Inhibiting Aβ Accumulation. 25714973 2015
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Identification of the key molecules involved in chronic copper exposure-aggravated memory impairment in transgenic mice of Alzheimer's disease using proteomic analysis. 25352456 2015
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Elevated serum pesticide levels and risk for Alzheimer disease. 24473795 2014
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Inhibition of human high-affinity copper importer Ctr1 orthologous in the nervous system of Drosophila ameliorates Aβ42-induced Alzheimer's disease-like symptoms. 23827522 2013
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. 24162737 2013
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human APP/PS1 transgenic mice treated with aluminum: an update of Alzheimer's disease model. 22507317 2012
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human pH-Dependent Cu(II) coordination to amyloid-β peptide: impact of sequence alterations, including the H6R and D7N familial mutations. 21980910 2011
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Increasing the predictive accuracy of amyloid-β blood-borne biomarkers in Alzheimer's disease. 21157020 2011
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Aβ40 oligomers identified as a potential biomarker for the diagnosis of Alzheimer's disease. 21209907 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human On the metal ion (Zn(2+), Cu(2+)) coordination with beta-amyloid peptide: DFT computational study. 20640797 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Early effects of aluminum chloride on beta-secretase mRNA expression in a neuronal model of beta-amyloid toxicity. 20111991 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Leptin reduces the accumulation of Abeta and phosphorylated tau induced by 27-hydroxycholesterol in rabbit organotypic slices. 20157255 2010
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Testosterone modifies the effect of APOE genotype on hippocampal volume in middle-aged men. 20819998 2010
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis. 19286555 2009
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human APP expression, distribution and accumulation are altered by aluminum in a rodent model for Alzheimer's disease. 19818510 2009
Entrez Id: 348
Gene Symbol: APOE
APOE 		0.500 Biomarker disease CTD_human Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. 19734902 2009
Entrez Id: 351
Gene Symbol: APP
APP 		0.500 Biomarker disease CTD_human Exposure to metal ions regulates mRNA levels of APP and BACE1 in PC12 cells: blockage by curcumin. 18583042 2008