Source: ALL
Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.310 Biomarker phenotype CTD_human Antinociceptive effects of nociceptin/orphanin FQ administered intrathecally in monkeys. 19231294 2009
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.310 Biomarker phenotype CTD_human Interaction of transient receptor potential vanilloid 4, integrin, and SRC tyrosine kinase in mechanical hyperalgesia. 18234883 2008
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1 		0.310 Biomarker phenotype CTD_human Cannabinoids desensitize capsaicin and mustard oil responses in sensory neurons via TRPA1 activation. 18234885 2008
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.310 Biomarker phenotype CTD_human Anti-inflammatory and analgesic effects of the sesquiterpene lactone budlein A in mice: inhibition of cytokine production-dependent mechanism. 17320857 2007
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.310 Biomarker phenotype CTD_human Antinociceptive action of the extract and the flavonoid quercitrin isolated from Bauhinia microstachya leaves. 16259764 2005
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.310 Biomarker phenotype CTD_human Antinociceptive properties of mixture of alpha-amyrin and beta-amyrin triterpenes: evidence for participation of protein kinase C and protein kinase A pathways. 15626726 2005
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		0.310 Biomarker phenotype CTD_human Involvement of substance P, CGRP and histamine in the hyperalgesia and cytokine upregulation induced by intraplantar injection of capsaicin in rats. 15265675 2004
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		0.310 Therapeutic phenotype CTD_human Involvement of substance P, CGRP and histamine in the hyperalgesia and cytokine upregulation induced by intraplantar injection of capsaicin in rats. 15265675 2004
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		0.310 Biomarker phenotype CTD_human Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain. 12787826 2003
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		0.310 Therapeutic phenotype CTD_human Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain. 12787826 2003
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		0.310 Biomarker phenotype CTD_human The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin. 12855330 2003
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.310 Biomarker phenotype CTD_human Pharmacological sensitivity and gene expression analysis of the tibial nerve injury model of neuropathic pain. 12787826 2003
Entrez Id: 796
Gene Symbol: CALCA
CALCA 		0.310 Therapeutic phenotype CTD_human The role of calcitonin gene-related peptide (CGRP) in the generation and maintenance of mechanical allodynia and hyperalgesia in rats after intradermal injection of capsaicin. 12855330 2003
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.310 Biomarker phenotype CTD_human Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants. 12727271 2003
Entrez Id: 7442
Gene Symbol: TRPV1
TRPV1 		0.310 Biomarker phenotype CTD_human Peripheral group II metabotropic glutamate receptors (mGluR2/3) regulate prostaglandin E2-mediated sensitization of capsaicin responses and thermal nociception. 12151517 2002
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.310 Biomarker phenotype CTD_human Hyperalgesia during opioid abstinence: mediation by glutamate and substance p. 12351280 2002
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.310 Biomarker phenotype CTD_human The involvement of K+ channels and Gi/o protein in the antinociceptive action of the gallic acid ethyl ester. 10499367 1999
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.310 Biomarker phenotype CTD_human Pharmacological modulation of secondary mediator systems--cyclic AMP and cyclic GMP--on inflammatory hyperalgesia. 10401557 1999
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.310 Biomarker phenotype CTD_human Anti-hyperalgesic properties of the extract and of the main sesquiterpene polygodial isolated from the barks of Drymis winteri (Winteraceae). 9714424 1998
Entrez Id: 6863
Gene Symbol: TAC1
TAC1 		0.310 Biomarker phenotype CTD_human Substance P and capsaicin-induced mechanical hyperalgesia in the rat knee joint; the involvement of bradykinin B1 and B2 receptors. 8864563 1996
Entrez Id: 3553
Gene Symbol: IL1B
IL1B 		0.310 Biomarker phenotype CTD_human Cytokine-mediated inflammatory hyperalgesia limited by interleukin-10. 7582491 1995
Entrez Id: 8912
Gene Symbol: CACNA1H
CACNA1H 		0.300 Biomarker phenotype CTD_human Critical role of Cav3.2 T-type calcium channels in the peripheral neuropathy induced by bortezomib, a proteasome-inhibiting chemotherapeutic agent, in mice. 30552955 2019
Entrez Id: 1394
Gene Symbol: CRHR1
CRHR1 		0.300 Biomarker phenotype CTD_human Role of CRF1 receptor in post-incisional plasma extravasation and nociceptive responses in mice. 28434951 2017
Entrez Id: 9927
Gene Symbol: MFN2
MFN2 		0.300 Biomarker phenotype CTD_human Involvement of Charcot-Marie-Tooth disease gene mitofusin 2 expression in paclitaxel-induced mechanical allodynia in rats. 28587902 2017
Entrez Id: 199
Gene Symbol: AIF1
AIF1 		0.300 Biomarker phenotype CTD_human Resveratrol suppresses glial activation and alleviates trigeminal neuralgia via activation of AMPK. 27093858 2016