Gene Score gda Association Type Type Original DB Sentence supporting the association PMID PMID Year
Entrez Id: 263
Gene Symbol: AMD1P2
AMD1P2
0.100 Biomarker disease BEFREE No significant differences in cytokine levels were observed between AMD and PCV patients for both plasma and aqueous humor. 30682207 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 AlteredExpression disease BEFREE This association was also found retrospectively in a larger sample of patients with neovascular AMD at 12 (ρ = 0.46; 95% CI, 0.16-0.68; P = .004), 24 (ρ = 0.49; 95% CI, 0.20-0.70; P = .002), and 36 (ρ = 0.65; 95% CI, 0.41-0.80; P < .001) months and patients with PCV at 12 (ρ = 0.27; 95% CI, -0.28 to 0.68; P = .30), 24 (ρ = 0.60; 95% CI, 0.12-0.85; P = .02), and 36 (ρ = 0.70; 95% CI, 0.27-0.90; P = .005) months, suggesting that this association is not specific to AMD but rather reflects VEGF activity in neovascularization. 30844038 2019
Entrez Id: 262
Gene Symbol: AMD1
AMD1
0.100 Biomarker disease BEFREE No significant differences in cytokine levels were observed between AMD and PCV patients for both plasma and aqueous humor. 30682207 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE Early retinal and choroidal effect of photodynamic treatment in patients with polypoidal choroidal vasculopathy with or without anti-vascular endothelial growth factor: An optical coherence tomography angiography study. 30352287 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE DIFFERENCE BETWEEN PACHYCHOROID AND NONPACHYCHOROID POLYPOIDAL CHOROIDAL VASCULOPATHY AND THEIR RESPONSE TO ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY. 31181038 2019
Entrez Id: 387715
Gene Symbol: ARMS2
ARMS2
0.100 GeneticVariation disease BEFREE The presence of the G allele at rs10490924 in the ARMS2 gene is likely associated with a lower chance of retreatment after IVA+PDT in patients with PCV. 31376050 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE Clinical Characteristics of Polypoidal Choroidal Vasculopathy and Anti-Vascular Endothelial Growth Factor Treatment Response in Caucasians. 31707394 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE Five-year real-world outcomes of anti-vascular endothelial growth factor monotherapy versus combination therapy for polypoidal choroidal vasculopathy in a Chinese population: a retrospective study. 31752769 2019
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE Dynamic changes in choroidal conditions during anti-vascular endothelial growth factor therapy in polypoidal choroidal vasculopathy. 31388029 2019
Entrez Id: 263
Gene Symbol: AMD1P2
AMD1P2
0.100 Biomarker disease BEFREE Whether PCV is a subtype of AMD or a distinct entity from nAMD remains unknown. 29323771 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE The Use of Vascular Endothelial Growth Factor Inhibitors and Complementary Treatment Options in Polypoidal Choroidal Vasculopathy: A Subtype of Neovascular Age-Related Macular Degeneration. 30177632 2018
Entrez Id: 262
Gene Symbol: AMD1
AMD1
0.100 Biomarker disease BEFREE Morphological Difference of Choroidal Vasculature Between Polypoidal Choroidal Vasculopathy and Neovascular AMD on OCT: From the Perspective of Pachychoroid. 30395671 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE MORPHOLOGIC FEATURES ASSOCIATED WITH FIBROTIC SCARRING AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY IN POLYPOIDAL CHOROIDAL VASCULOPATHY. 28930802 2018
Entrez Id: 263
Gene Symbol: AMD1P2
AMD1P2
0.100 Biomarker disease BEFREE Fellow eyes of patients with classic exudative AMD had greater foveal avascular zone area and smaller VD values of the deep retinal capillary plexus than those with polypoidal choroidal vasculopathy (P < 0.001, P = 0.004). 30383196 2018
Entrez Id: 263
Gene Symbol: AMD1P2
AMD1P2
0.100 Biomarker disease BEFREE Morphological Difference of Choroidal Vasculature Between Polypoidal Choroidal Vasculopathy and Neovascular AMD on OCT: From the Perspective of Pachychoroid. 30395671 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE To investigate the influence of choroidal vascular hyperpermeability (CVH) and choroidal thickness on treatment outcomes in eyes with polypoidal choroidal vasculopathy (PCV) undergoing anti-vascular endothelial growth factor monotherapy or combination therapy of photodynamic therapy and anti-vascular endothelial growth factor injections. 28704255 2018
Entrez Id: 262
Gene Symbol: AMD1
AMD1
0.100 Biomarker disease BEFREE Whether PCV is a subtype of AMD or a distinct entity from nAMD remains unknown. 29323771 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE COMPARISON OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHIC CHANGES AFTER ANTI-VASCULAR ENDOTHELIAL GROWTH FACTOR THERAPY ALONE OR IN COMBINATION WITH PHOTODYNAMIC THERAPY IN POLYPOIDAL CHOROIDAL VASCULOPATHY. 28767554 2018
Entrez Id: 262
Gene Symbol: AMD1
AMD1
0.100 Biomarker disease BEFREE Fellow eyes of patients with classic exudative AMD had greater foveal avascular zone area and smaller VD values of the deep retinal capillary plexus than those with polypoidal choroidal vasculopathy (P < 0.001, P = 0.004). 30383196 2018
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE To evaluate the 6-year outcomes of anti-VEGF (vascular endothelial growth factor) monotherapy for polypoidal choroidal vasculopathy (PCV). 28546150 2018
Entrez Id: 262
Gene Symbol: AMD1
AMD1
0.100 Biomarker disease BEFREE Current results implied that choroidal hemodynamics may be relevant to variable natural history and treatment response in neovascular AMD and polypoidal choroidal vasculopathy. 28195603 2017
Entrez Id: 263
Gene Symbol: AMD1P2
AMD1P2
0.100 Biomarker disease BEFREE Overall, CD11b+ monocytes were both increased in patients with PCV and neovascular AMD. 29049725 2017
Entrez Id: 263
Gene Symbol: AMD1P2
AMD1P2
0.100 Biomarker disease BEFREE On SS-OCT-A, flow signals with vascular network configuration were detected in 81.2% and 77.8% of eyes with t-AMD and PCV, respectively. 27828911 2017
Entrez Id: 7422
Gene Symbol: VEGFA
VEGFA
0.100 Biomarker disease BEFREE Combined therapy versus anti-vascular endothelial growth factor monotherapy for polypoidal choroidal vasculopathy: a Meta-analysis. 28861356 2017
Entrez Id: 262
Gene Symbol: AMD1
AMD1
0.100 Biomarker disease BEFREE Overall, CD11b+ monocytes were both increased in patients with PCV and neovascular AMD. 29049725 2017