Disease: Scleroderma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
COL1A1 P02452 collagen type I alpha 1 chain 1.00 0.430 0.808
COL3A1 P02461 collagen type III alpha 1 chain 1.00 0.477 0.808
EZH2 Q15910 enhancer of zeste 2 polycomb repressive complex 2 subunit Epigenetic regulator 1.00 0.376 0.885
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
HDAC5 Q9UQL6 histone deacetylase 5 Epigenetic regulator 1.00 0.552 0.769
THBS1 P07996 thrombospondin 1 1.00 0.407 0.885
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
KLF4 O43474 Kruppel like factor 4 Nucleic acid binding 1.00 0.449 0.769
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
SMAD2 Q15796 SMAD family member 2 Transcription factor 1.00 0.456 0.808
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
LOX P28300 lysyl oxidase 0.99 0.447 0.846
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
TIMP3 P35625 TIMP metallopeptidase inhibitor 3 Enzyme modulator 0.63 0.445 0.923
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IL2 P60568 interleukin 2 0.48 0.336 0.885
S100A9 P06702 S100 calcium binding protein A9 Calcium-binding protein 0.48 0.433 0.885
IFNG P01579 interferon gamma 0.47 0.288 0.962