Disease: Scleroderma
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
EDN1 P05305 endothelin 1 Signaling 0.46 0.380 0.846
MAPK14 Q16539 mitogen-activated protein kinase 14 Kinase 0.37 0.379 0.923
EGR1 P18146 early growth response 1 Nucleic acid binding 0.35 0.433 0.923
IL6 P05231 interleukin 6 0.32 0.248 0.962
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
LTB4R Q15722 leukotriene B4 receptor G-protein coupled receptor 0.12 0.576 0.692
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
IL17A Q16552 interleukin 17A 4.3E-02 0.324 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
PPARG P37231 peroxisome proliferator activated receptor gamma Nuclear receptor 2.9E-02 0.358 0.885
IL13 P35225 interleukin 13 1.4E-02 0.386 0.846
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
FN1 P02751 fibronectin 1 Signaling 1.4E-03 0.365 0.962
HLA-DRB1 P01911 major histocompatibility complex, class II, DR beta 1 Immune response 1.1E-03 0.333 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
VEGFA P15692 vascular endothelial growth factor A Signaling 2.4E-05 0.266 0.923
LGALS3 P17931 galectin 3 Signaling 2.3E-05 0.392 0.846
ALOX5 P09917 arachidonate 5-lipoxygenase Enzyme 1.2E-06 0.447 0.885
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
TNC P24821 tenascin C 1.3E-07 0.433 0.846
TLR4 O00206 toll like receptor 4 4.6E-09 0.321 0.962
COMP P49747 cartilage oligomeric matrix protein 1.3E-09 0.503 0.808
CAT P04040 catalase Enzyme 1.6E-10 0.359 0.962