Disease: bone destruction
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNFRSF11A Q9Y6Q6 TNF receptor superfamily member 11a 8.8E-03 0.480 0.846
GRAP2 O75791 GRB2 related adaptor protein 2 1.5E-04 0.394 0.923
AHSA1 O95433 activator of HSP90 ATPase activity 1 1.00 0.396 0.923
DKK1 O94907 dickkopf WNT signaling pathway inhibitor 1 0.17 0.439 0.885
POLDIP2 Q9Y2S7 DNA polymerase delta interacting protein 2 0.41 0.396 0.923
IL17B Q9UHF5 interleukin 17B 3.4E-02 0.553 0.769
IL20 Q9NYY1 interleukin 20 1.3E-06 0.556 0.769
SOST Q9BQB4 sclerostin 0.87 0.474 0.808
ASCC2 Q9H1I8 activating signal cointegrator 1 complex subunit 2 3.1E-02 0.633 0.615
TPX2 Q9ULW0 TPX2 microtubule nucleation factor Cellular structure 1.00 0.541 0.692
CTSK P43235 cathepsin K Enzyme 3.1E-05 0.497 0.808
TYMP P19971 thymidine phosphorylase Enzyme 1.2E-04 0.495 0.769
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
MMP3 P08254 matrix metallopeptidase 3 Enzyme 5.7E-15 0.408 0.885
MMP7 P09237 matrix metallopeptidase 7 Enzyme 1.0E-09 0.446 0.885
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
MMP13 P45452 matrix metallopeptidase 13 Enzyme 7.9E-18 0.452 0.923
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
OAS3 Q9Y6K5 2'-5'-oligoadenylate synthetase 3 Enzyme 2.0E-33 0.608 0.615
SCO2 O43819 synthesis of cytochrome C oxidase 2 Enzyme 7.5E-07 0.479 0.846
HPSE Q9Y251 heparanase Enzyme 2.3E-14 0.425 0.808
RNF19A Q9NV58 ring finger protein 19A, RBR E3 ubiquitin protein ligase Enzyme 2.5E-02 0.397 0.923
SDC1 P18827 syndecan 1 Extracellular structure 8.4E-03 0.445 0.769
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
B2M P61769 beta-2-microglobulin Immune response 0.56 0.447 0.846