Disease: Bicuspid aortic valve
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885
LOX P28300 lysyl oxidase 0.99 0.447 0.846
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
LIMK1 P53667 LIM domain kinase 1 Kinase 1.00 0.488 0.731
APLN Q9ULZ1 apelin 0.46 0.497 0.769
TGFB3 P10600 transforming growth factor beta 3 Signaling 0.99 0.498 0.808
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808
ACTA2 P62736 actin alpha 2, smooth muscle Cellular structure 0.93 0.508 0.846
MYLK Q15746 myosin light chain kinase Kinase 9.2E-12 0.510 0.846