Disease: Bicuspid aortic valve
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
ELN P15502 elastin 2.1E-14 0.415 0.885
MYLK Q15746 myosin light chain kinase Kinase 9.2E-12 0.510 0.846
ABCC9 O60706 ATP binding cassette subfamily C member 9 Transporter 9.4E-09 0.552 0.692
B3GAT3 O94766 beta-1,3-glucuronyltransferase 3 Enzyme 2.7E-08 0.621 0.538
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769
TBL2 Q9Y4P3 transducin beta like 2 1.8E-04 0.538 0.731
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
MFAP5 Q13361 microfibril associated protein 5 5.1E-03 0.590 0.615
CHST3 Q7LGC8 carbohydrate sulfotransferase 3 7.2E-03 0.517 0.846
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
FOXE3 Q13461 forkhead box E3 Transcription factor 0.18 0.568 0.654
APLN Q9ULZ1 apelin 0.46 0.497 0.769
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
SMAD3 P84022 SMAD family member 3 Transcription factor 0.80 0.415 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
GTF2IRD1 Q9UHL9 GTF2I repeat domain containing 1 0.90 0.522 0.769