Disease: Bicuspid aortic valve
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ABCC9 O60706 ATP binding cassette subfamily C member 9 Transporter 9.4E-09 0.552 0.692
B3GAT3 O94766 beta-1,3-glucuronyltransferase 3 Enzyme 2.7E-08 0.621 0.538
AGT P01019 angiotensinogen Enzyme modulator 5.0E-08 0.367 0.923
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
MMP2 P08253 matrix metallopeptidase 2 Enzyme 0.84 0.333 0.923
TGFB3 P10600 transforming growth factor beta 3 Signaling 0.99 0.498 0.808
MMP9 P14780 matrix metallopeptidase 9 Enzyme 1.9E-17 0.305 0.923
ELN P15502 elastin 2.1E-14 0.415 0.885
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
LOX P28300 lysyl oxidase 0.99 0.447 0.846
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885
MAT2A P31153 methionine adenosyltransferase 2A Enzyme 1.00 0.615 0.654
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769
FBN1 P35555 fibrillin 1 Calcium-binding protein 1.00 0.417 0.846
MYH11 P35749 myosin heavy chain 11 0.77 0.528 0.731
TGFBR1 P36897 transforming growth factor beta receptor 1 Kinase 0.85 0.451 0.885
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
GATA4 P43694 GATA binding protein 4 0.49 0.458 0.846
NKX2-5 P52952 NK2 homeobox 5 Transcription factor 0.95 0.533 0.692
LIMK1 P53667 LIM domain kinase 1 Kinase 1.00 0.488 0.731
TGFB2 P61812 transforming growth factor beta 2 Signaling 1.00 0.433 0.885