Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
FIP1L1 Q6UN15 factor interacting with PAPOLA and CPSF1 0.79 0.575 0.577
FLT3 P36888 fms related receptor tyrosine kinase 3 Kinase 0.61 0.462 0.654
THPO P40225 thrombopoietin 0.20 0.513 0.692
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
ETV6 P41212 ETS variant transcription factor 6 Transcription factor 0.97 0.477 0.731
MECOM Q03112 MDS1 and EVI1 complex locus 1.00 0.513 0.731
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
FANCB Q8NB91 FA complementation group B 1.00 0.468 0.769
MVD P53602 mevalonate diphosphate decarboxylase 2.7E-17 0.568 0.769
PTPN6 P29350 protein tyrosine phosphatase non-receptor type 6 1.00 0.485 0.769
RUNX1 Q01196 RUNX family transcription factor 1 Transcription factor 0.65 0.425 0.808
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
STAT5A P42229 signal transducer and activator of transcription 5A Nucleic acid binding 1.00 0.445 0.808
STAT5B P51692 signal transducer and activator of transcription 5B Nucleic acid binding 1.00 0.442 0.808
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808