Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR150 microRNA 150 0.455 0.808
MIR223 microRNA 223 0.433 0.808
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
SF3B1 O75533 splicing factor 3b subunit 1 Nucleic acid binding 1.00 0.511 0.731
ABL1 P00519 ABL proto-oncogene 1, non-receptor tyrosine kinase Kinase 1.00 0.432 0.923
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
CSF2 P04141 colony stimulating factor 2 Signaling 0.83 0.330 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
PDGFRB P09619 platelet derived growth factor receptor beta Kinase 0.90 0.416 0.846
U2AF1 P0DN76 Q01081 U2 small nuclear RNA auxiliary factor 1 Nucleic acid binding 0.99 0.604 0.577
AR P10275 androgen receptor Nuclear receptor 0.99 0.351 0.846
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
BCR P11274 BCR activator of RhoGEF and GTPase Enzyme modulator 0.99 0.431 0.885
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
KITLG P21583 KIT ligand 0.85 0.473 0.885
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
CALR P27797 calreticulin Calcium-binding protein 0.89 0.413 0.923