Disease: Juvenile Myelomonocytic Leukemia
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
MIR150 microRNA 150 0.455 0.808
MIR223 microRNA 223 0.433 0.808
TET2 Q6N021 tet methylcytosine dioxygenase 2 4.3E-54 0.458 0.808
DNMT3A Q9Y6K1 DNA methyltransferase 3 alpha 7.4E-39 0.445 0.846
MVD P53602 mevalonate diphosphate decarboxylase 2.7E-17 0.568 0.769
SGSM3 Q96HU1 small G protein signaling modulator 3 Enzyme 3.4E-15 0.469 0.808
ASXL1 Q8IXJ9 ASXL transcriptional regulator 1 1.3E-14 0.482 0.808
SOAT1 P35610 sterol O-acyltransferase 1 Enzyme 7.4E-10 0.424 0.846
IL3 P08700 interleukin 3 2.6E-09 0.489 0.731
PIK3CG P48736 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma Kinase 1.4E-06 0.320 0.885
CD34 P28906 CD34 molecule 5.0E-06 0.368 0.808
JAK3 P52333 Janus kinase 3 Kinase 5.9E-06 0.505 0.731
IL18R1 Q13478 interleukin 18 receptor 1 Receptor 8.6E-06 0.473 0.808
REG1A P05451 regenerating family member 1 alpha 1.3E-05 0.467 0.846
SH2B3 Q9UQQ2 SH2B adaptor protein 3 1.0E-04 0.527 0.692
CBL P22681 Cbl proto-oncogene Enzyme 6.1E-04 0.527 0.769
EPO P01588 erythropoietin 1.1E-02 0.381 0.885
CCR7 P32248 C-C motif chemokine receptor 7 G-protein coupled receptor 5.8E-02 0.443 0.769
EBI3 Q14213 Epstein-Barr virus induced 3 Signaling 0.11 0.474 0.808
THPO P40225 thrombopoietin 0.20 0.513 0.692
IL23A Q9NPF7 interleukin 23 subunit alpha Signaling 0.36 0.415 0.846
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
SRSF2 Q01130 serine and arginine rich splicing factor 2 Nucleic acid binding 0.48 0.561 0.731
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962