Disease: Tauopathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ACTB P60709 actin beta Cellular structure 0.99 0.325 0.923
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
ACHE P22303 acetylcholinesterase (Cartwright blood group) Enzyme 1.00 0.445 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
KHDRBS1 Q07666 KH RNA binding domain containing, signal transduction associated 1 Nucleic acid binding 0.99 0.457 0.846
HDAC6 Q9UBN7 histone deacetylase 6 Epigenetic regulator 1.00 0.465 0.846
GTF2H1 P32780 general transcription factor IIH subunit 1 Transcription factor 0.99 0.469 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
NUP62 P37198 nucleoporin 62 Transporter 0.95 0.470 0.885