Disease: Tauopathies
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NEFL P07196 neurofilament light 0.488 0.769
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
CAST P20810 calpastatin 4.1E-12 0.541 0.846
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
HSPB1 P04792 heat shock protein family B (small) member 1 2.8E-07 0.436 0.808
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
AIF1 P55008 allograft inflammatory factor 1 Calcium-binding protein 1.9E-06 0.521 0.808
HSPB3 Q12988 heat shock protein family B (small) member 3 6.1E-05 0.448 0.769
HSPB2 Q16082 heat shock protein family B (small) member 2 3.3E-04 0.457 0.769
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
APOE P02649 apolipoprotein E 1.9E-03 0.338 0.962
EIF2AK3 Q9NZJ5 eukaryotic translation initiation factor 2 alpha kinase 3 Kinase 2.8E-03 0.501 0.808
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
GH1 P01241 growth hormone 1 Signaling 3.0E-02 0.373 0.923
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
TIA1 P31483 TIA1 cytotoxic granule associated RNA binding protein 0.27 0.595 0.577
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962