Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
OGA | O60502 | O-GlcNAcase | 0.97 | 0.534 | 0.731 | |
SOD1 | P00441 | superoxide dismutase 1 | Enzyme | 0.18 | 0.379 | 0.962 |
GH1 | P01241 | growth hormone 1 | Signaling | 3.0E-02 | 0.373 | 0.923 |
TNF | P01375 | tumor necrosis factor | Signaling | 0.80 | 0.231 | 0.962 |
APOE | P02649 | apolipoprotein E | 1.9E-03 | 0.338 | 0.962 | |
TP53 | P04637 | tumor protein p53 | Transcription factor | 0.53 | 0.236 | 0.962 |
HSPB1 | P04792 | heat shock protein family B (small) member 1 | 2.8E-07 | 0.436 | 0.808 | |
IGF1 | P05019 | insulin like growth factor 1 | 0.27 | 0.318 | 0.885 | |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
NEFL | P07196 | neurofilament light | 0.488 | 0.769 | ||
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
GFAP | P14136 | glial fibrillary acidic protein | 1.5E-06 | 0.421 | 0.885 | |
CAST | P20810 | calpastatin | 4.1E-12 | 0.541 | 0.846 | |
ACHE | P22303 | acetylcholinesterase (Cartwright blood group) | Enzyme | 1.00 | 0.445 | 0.885 |
BDNF | P23560 | brain derived neurotrophic factor | Signaling | 0.66 | 0.345 | 0.923 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
TIA1 | P31483 | TIA1 cytotoxic granule associated RNA binding protein | 0.27 | 0.595 | 0.577 | |
GTF2H1 | P32780 | general transcription factor IIH subunit 1 | Transcription factor | 0.99 | 0.469 | 0.846 |
FUS | P35637 | FUS RNA binding protein | Nucleic acid binding | 1.00 | 0.470 | 0.846 |
IGFALS | P35858 | insulin like growth factor binding protein acid labile subunit | Receptor | 5.4E-11 | 0.511 | 0.846 |
NUP62 | P37198 | nucleoporin 62 | Transporter | 0.95 | 0.470 | 0.885 |
SNCA | P37840 | synuclein alpha | Transporter | 0.88 | 0.427 | 0.885 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
AIF1 | P55008 | allograft inflammatory factor 1 | Calcium-binding protein | 1.9E-06 | 0.521 | 0.808 |
ACTB | P60709 | actin beta | Cellular structure | 0.99 | 0.325 | 0.923 |