Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
MLH1 P40692 mutL homolog 1 Nucleic acid binding 3.4E-05 0.399 0.808
MSH2 P43246 mutS homolog 2 Nucleic acid binding 0.90 0.406 0.808
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
ELN P15502 elastin 2.1E-14 0.415 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
MSH6 P52701 mutS homolog 6 Nucleic acid binding 3.7E-05 0.462 0.731
NF2 P35240 neurofibromin 2 1.00 0.468 0.885
VCP P55072 valosin containing protein 1.00 0.469 0.923
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PMS2 P54278 PMS1 homolog 2, mismatch repair system component Nucleic acid binding 4.5E-27 0.484 0.808
LIMK1 P53667 LIM domain kinase 1 Kinase 1.00 0.488 0.731
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
GTF2I P78347 general transcription factor IIi 1.00 0.500 0.808
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
RFC2 P35250 replication factor C subunit 2 Enzyme 2.2E-06 0.520 0.769
GTF2IRD1 Q9UHL9 GTF2I repeat domain containing 1 0.90 0.522 0.769
BMPR1A P36894 bone morphogenetic protein receptor type 1A Kinase 0.90 0.522 0.731
CLIP2 Q9UDT6 CAP-Gly domain containing linker protein 2 Cellular structure 1.00 0.529 0.808
KMT2B Q9UMN6 lysine methyltransferase 2B 1.00 0.529 0.808