Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
ABCA7 | Q8IZY2 | ATP binding cassette subfamily A member 7 | Transporter | 2.1E-55 | 0.644 | 0.577 |
PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
FAN1 | Q9Y2M0 | FANCD2 and FANCI associated nuclease 1 | 1.7E-25 | 0.610 | 0.577 | |
VPS13A | Q96RL7 | vacuolar protein sorting 13 homolog A | 9.3E-22 | 0.650 | 0.577 | |
PMS1 | P54277 | PMS1 homolog 1, mismatch repair system component | Nucleic acid binding | 1.3E-17 | 0.569 | 0.654 |
ELN | P15502 | elastin | 2.1E-14 | 0.415 | 0.885 | |
SORL1 | Q92673 | sortilin related receptor 1 | Transporter | 7.7E-11 | 0.582 | 0.692 |
TREM2 | Q9NZC2 | triggering receptor expressed on myeloid cells 2 | 3.3E-09 | 0.519 | 0.769 | |
MLH3 | Q9UHC1 | mutL homolog 3 | Nucleic acid binding | 4.9E-08 | 0.582 | 0.538 |
EPCAM | P16422 | epithelial cell adhesion molecule | 1.3E-07 | 0.451 | 0.885 | |
C9orf72 | Q96LT7 | C9orf72-SMCR8 complex subunit | 1.1E-06 | 0.496 | 0.769 | |
RFC2 | P35250 | replication factor C subunit 2 | Enzyme | 2.2E-06 | 0.520 | 0.769 |
CHMP2B | Q9UQN3 | charged multivesicular body protein 2B | 4.6E-06 | 0.543 | 0.731 | |
SEMA4A | Q9H3S1 | semaphorin 4A | Signaling | 1.8E-05 | 0.569 | 0.692 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
TBL2 | Q9Y4P3 | transducin beta like 2 | 1.8E-04 | 0.538 | 0.731 | |
PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
SPG21 | Q9NZD8 | SPG21 abhydrolase domain containing, maspardin | 6.6E-04 | 0.695 | 0.500 | |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 | |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
RPS20 | P60866 | ribosomal protein S20 | Nucleic acid binding | 2.1E-02 | 0.610 | 0.692 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 |