Gene | Uniprot | Gene Full Name | Protein Class | pLI | DSI v | DPI v |
---|---|---|---|---|---|---|
KCNQ2 | O43526 | potassium voltage-gated channel subfamily Q member 2 | Ion channel | 1.00 | 0.537 | 0.654 |
TOMM40 | O96008 | translocase of outer mitochondrial membrane 40 | Transporter | 0.99 | 0.590 | 0.538 |
KRAS | P01116 | KRAS proto-oncogene, GTPase | Enzyme modulator | 7.9E-04 | 0.320 | 0.923 |
APP | P05067 | amyloid beta precursor protein | Enzyme modulator | 4.7E-02 | 0.422 | 0.846 |
MAPT | P10636 | microtubule associated protein tau | 6.0E-03 | 0.446 | 0.923 | |
ELN | P15502 | elastin | 2.1E-14 | 0.415 | 0.885 | |
EPCAM | P16422 | epithelial cell adhesion molecule | 1.3E-07 | 0.451 | 0.885 | |
GRN | P28799 | granulin precursor | 7.0E-02 | 0.435 | 0.846 | |
NF2 | P35240 | neurofibromin 2 | 1.00 | 0.468 | 0.885 | |
RFC2 | P35250 | replication factor C subunit 2 | Enzyme | 2.2E-06 | 0.520 | 0.769 |
BMPR1A | P36894 | bone morphogenetic protein receptor type 1A | Kinase | 0.90 | 0.522 | 0.731 |
TGFBR2 | P37173 | transforming growth factor beta receptor 2 | Kinase | 0.13 | 0.413 | 0.846 |
MLH1 | P40692 | mutL homolog 1 | Nucleic acid binding | 3.4E-05 | 0.399 | 0.808 |
PIK3CA | P42336 | phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha | Kinase | 1.00 | 0.292 | 0.923 |
MSH2 | P43246 | mutS homolog 2 | Nucleic acid binding | 0.90 | 0.406 | 0.808 |
PSEN1 | P49768 | presenilin 1 | Enzyme | 0.97 | 0.469 | 0.846 |
PSEN2 | P49810 | presenilin 2 | Enzyme | 5.4E-04 | 0.550 | 0.654 |
MSH6 | P52701 | mutS homolog 6 | Nucleic acid binding | 3.7E-05 | 0.462 | 0.731 |
LIMK1 | P53667 | LIM domain kinase 1 | Kinase | 1.00 | 0.488 | 0.731 |
PMS1 | P54277 | PMS1 homolog 1, mismatch repair system component | Nucleic acid binding | 1.3E-17 | 0.569 | 0.654 |
PMS2 | P54278 | PMS1 homolog 2, mismatch repair system component | Nucleic acid binding | 4.5E-27 | 0.484 | 0.808 |
VCP | P55072 | valosin containing protein | 1.00 | 0.469 | 0.923 | |
RPS20 | P60866 | ribosomal protein S20 | Nucleic acid binding | 2.1E-02 | 0.610 | 0.692 |
GTF2I | P78347 | general transcription factor IIi | 1.00 | 0.500 | 0.808 | |
SQSTM1 | Q13501 | sequestosome 1 | 8.6E-04 | 0.428 | 0.885 |