Disease: Hyperalgesia, Thermal
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
IL4 P05112 interleukin 4 4.7E-03 0.332 0.962
IL10 P22301 interleukin 10 5.9E-03 0.281 0.923
PNOC Q13519 prepronociceptin Signaling 1.5E-02 0.603 0.577
CALCA P01258 P06881 calcitonin related polypeptide alpha Signaling 1.6E-02 0.416 0.923
IL1RN P18510 interleukin 1 receptor antagonist 3.1E-02 0.373 0.923
MAPK3 P27361 mitogen-activated protein kinase 3 Kinase 3.7E-02 0.379 0.885
SIRT1 Q96EB6 sirtuin 1 Epigenetic regulator 8.7E-02 0.378 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
CDK5 Q00535 cyclin dependent kinase 5 Kinase 0.14 0.495 0.846
GJA1 P17302 gap junction protein alpha 1 Cell-cell junction 0.16 0.393 0.885
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
FOS P01100 Fos proto-oncogene, AP-1 transcription factor subunit Transcription factor 0.26 0.411 0.885
IL6 P05231 interleukin 6 0.32 0.248 0.962
S100A9 P06702 S100 calcium binding protein A9 Calcium-binding protein 0.48 0.433 0.885
CNR1 P21554 cannabinoid receptor 1 G-protein coupled receptor 0.51 0.446 0.808
CCL2 P13500 C-C motif chemokine ligand 2 Signaling 0.61 0.321 0.962
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
PTGES O14684 prostaglandin E synthase 0.71 0.540 0.769
TAC1 P20366 tachykinin precursor 1 0.75 0.424 0.923
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
NGF P01138 nerve growth factor Signaling 0.82 0.391 0.885
HMGB1 P09429 high mobility group box 1 Nucleic acid binding 0.82 0.368 0.923
GRIN1 Q05586 glutamate ionotropic receptor NMDA type subunit 1 Ion channel 0.98 0.561 0.692
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
CSF1 P09603 colony stimulating factor 1 1.00 0.473 0.808