Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
TSPO P30536 translocator protein 2.7E-04 0.444 0.885
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
LEP P41159 leptin 0.46 0.349 0.846
HTT P42858 huntingtin 1.00 0.548 0.654
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654
CDR1 P51861 cerebellar degeneration related protein 1 0.576 0.808
VCP P55072 valosin containing protein 1.00 0.469 0.923
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
DCTN1 Q14203 dynactin subunit 1 Chaperone 8.4E-02 0.597 0.500
SNCB Q16143 synuclein beta Transporter 6.8E-02 0.619 0.577
NFE2L2 Q16236 nuclear factor, erythroid 2 like 2 Enzyme 3.6E-03 0.357 0.885
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
RBMS3 Q6XE24 RNA binding motif single stranded interacting protein 3 0.21 0.553 0.692
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808