Disease: Frontotemporal Lobar Degeneration
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
IGFALS P35858 insulin like growth factor binding protein acid labile subunit Receptor 5.4E-11 0.511 0.846
LEP P41159 leptin 0.46 0.349 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
TBK1 Q9UHD2 TANK binding kinase 1 Kinase 7.5E-02 0.513 0.846
RUNX1T1 Q06455 RUNX1 partner transcriptional co-repressor 1 Transcription factor 0.98 0.530 0.808
CDR1 P51861 cerebellar degeneration related protein 1 0.576 0.808
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
HCRT O43612 hypocretin neuropeptide precursor 2.9E-02 0.500 0.808
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808
SIGMAR1 Q99720 sigma non-opioid intracellular receptor 1 0.17 0.544 0.808
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
LRRK2 Q5S007 leucine rich repeat kinase 2 Kinase 2.6E-30 0.510 0.808
NEFL P07196 neurofilament light 0.488 0.769
PTBP1 P26599 polypyrimidine tract binding protein 1 1.00 0.517 0.769
TREM2 Q9NZC2 triggering receptor expressed on myeloid cells 2 3.3E-09 0.519 0.769
C9orf72 Q96LT7 C9orf72-SMCR8 complex subunit 1.1E-06 0.496 0.769
CHMP2B Q9UQN3 charged multivesicular body protein 2B 4.6E-06 0.543 0.731
NPC1 O15118 NPC intracellular cholesterol transporter 1 Transporter 6.5E-06 0.518 0.692
SRRM2 Q9UQ35 serine/arginine repetitive matrix 2 1.00 0.564 0.692
RBMS3 Q6XE24 RNA binding motif single stranded interacting protein 3 0.21 0.553 0.692
HTT P42858 huntingtin 1.00 0.548 0.654
PSEN2 P49810 presenilin 2 Enzyme 5.4E-04 0.550 0.654