Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TARDBP Q13148 TAR DNA binding protein 0.99 0.493 0.808
NEFL P07196 neurofilament light 0.488 0.769
ATXN2 Q99700 ataxin 2 Nucleic acid binding 0.85 0.482 0.808
SYP P08247 synaptophysin Transporter 0.92 0.481 0.808
FUS P35637 FUS RNA binding protein Nucleic acid binding 1.00 0.470 0.846
PSEN1 P49768 presenilin 1 Enzyme 0.97 0.469 0.846
VCP P55072 valosin containing protein 1.00 0.469 0.923
CP P00450 ceruloplasmin Enzyme 4.2E-10 0.466 0.846
SLC6A3 Q01959 solute carrier family 6 member 3 Transporter 1.00 0.453 0.885
MAPT P10636 microtubule associated protein tau 6.0E-03 0.446 0.923
PRNP F7VJQ1 P04156 prion protein 6.3E-04 0.445 0.923
TSPO P30536 translocator protein 2.7E-04 0.444 0.885
CST3 P01034 cystatin C 3.9E-03 0.436 0.808
HFE Q30201 homeostatic iron regulator 2.6E-08 0.436 0.846
GRN P28799 granulin precursor 7.0E-02 0.435 0.846
SLC6A4 P31645 solute carrier family 6 member 4 Transporter 0.25 0.429 0.808
SQSTM1 Q13501 sequestosome 1 8.6E-04 0.428 0.885
SNCA P37840 synuclein alpha Transporter 0.88 0.427 0.885
APP P05067 amyloid beta precursor protein Enzyme modulator 4.7E-02 0.422 0.846
GFAP P14136 glial fibrillary acidic protein 1.5E-06 0.421 0.885
NOS1 P29475 nitric oxide synthase 1 1.00 0.408 0.885
LAMC2 Q13753 laminin subunit gamma 2 Enzyme modulator 2.9E-12 0.389 0.923
SOD1 P00441 superoxide dismutase 1 Enzyme 0.18 0.379 0.962
SOD2 P04179 superoxide dismutase 2 Enzyme 0.15 0.379 0.923
NOS3 P29474 nitric oxide synthase 3 6.7E-07 0.378 0.885