Disease: Metastatic non-small cell lung cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ACKR3 P25106 atypical chemokine receptor 3 G-protein coupled receptor 0.39 0.428 0.885
ALK Q9UM73 ALK receptor tyrosine kinase Kinase 3.2E-06 0.396 0.846
ATM Q13315 ATM serine/threonine kinase Kinase 5.6E-47 0.374 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CDH1 P12830 cadherin 1 0.15 0.401 0.808
CDK2 P24941 cyclin dependent kinase 2 Kinase 0.61 0.456 0.692
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
CEACAM5 P06731 CEA cell adhesion molecule 5 4.2E-10 0.420 0.846
CRP P02741 C-reactive protein 3.7E-03 0.299 0.962
CTLA4 P16410 cytotoxic T-lymphocyte associated protein 4 0.94 0.369 0.923
CXCL12 P48061 C-X-C motif chemokine ligand 12 0.12 0.379 0.846
CXCR4 P61073 C-X-C motif chemokine receptor 4 G-protein coupled receptor 1.8E-02 0.362 0.923
CYP2C19 P33261 cytochrome P450 family 2 subfamily C member 19 6.5E-20 0.467 0.846
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
EPCAM P16422 epithelial cell adhesion molecule 1.3E-07 0.451 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERCC1 P07992 ERCC excision repair 1, endonuclease non-catalytic subunit Enzyme 1.6E-07 0.445 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
FOXM1 Q08050 forkhead box M1 7.4E-04 0.441 0.769
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
ITGAV P06756 integrin subunit alpha V 2.3E-04 0.526 0.769
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
KISS1 Q15726 KiSS-1 metastasis suppressor 0.49 0.507 0.808