Disease: Major Depressive Disorder
Source: CURATED ×
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
ADCY7 P51828 adenylate cyclase 7 9.5E-07 0.656 0.462
BDNF P23560 brain derived neurotrophic factor Signaling 0.66 0.345 0.923
CACNA1C Q13936 calcium voltage-gated channel subunit alpha1 C Ion channel 1.00 0.510 0.846
CLOCK O15516 clock circadian regulator 1.00 0.463 0.885
COMT P21964 catechol-O-methyltransferase Enzyme 1.1E-06 0.400 0.923
CREB1 P16220 cAMP responsive element binding protein 1 1.00 0.463 0.885
CRH P06850 corticotropin releasing hormone Signaling 0.72 0.439 0.808
CRHBP P24387 corticotropin releasing hormone binding protein Signaling 0.21 0.659 0.500
CRHR1 P34998 corticotropin releasing hormone receptor 1 3.8E-05 0.517 0.769
CYP2D6 P10635 cytochrome P450 family 2 subfamily D member 6 1.1E-25 0.437 0.885
DAOA P59103 D-amino acid oxidase activator 1.4E-04 0.678 0.346
DBH P09172 dopamine beta-hydroxylase 3.3E-10 0.511 0.846
DISC1 Q9NRI5 DISC1 scaffold protein 1.7E-06 0.548 0.769
DLG3 Q92796 discs large MAGUK scaffold protein 3 1.00 0.544 0.615
DLG4 P78352 discs large MAGUK scaffold protein 4 Receptor 1.00 0.595 0.654
DRD2 P14416 dopamine receptor D2 G-protein coupled receptor 0.75 0.436 0.846
DRD3 P35462 dopamine receptor D3 G-protein coupled receptor 2.4E-03 0.529 0.692
DRD4 P21917 dopamine receptor D4 G-protein coupled receptor 9.3E-09 0.517 0.577
DTNBP1 Q96EV8 dystrobrevin binding protein 1 6.8E-06 0.588 0.615
FKBP5 Q13451 FKBP prolyl isomerase 5 Enzyme 0.73 0.524 0.769
GAD1 Q99259 glutamate decarboxylase 1 Enzyme 4.6E-02 0.486 0.885
GAD2 Q05329 glutamate decarboxylase 2 Enzyme 0.75 0.529 0.731
GAL P22466 galanin and GMAP prepropeptide 4.4E-06 0.493 0.846
GNB3 P16520 G protein subunit beta 3 Enzyme 3.3E-11 0.518 0.808
GSK3B P49841 glycogen synthase kinase 3 beta Kinase 0.96 0.430 0.846