Disease: Ichthyosis, X-Linked
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
STAT3 P40763 signal transducer and activator of transcription 3 Nucleic acid binding 1.00 0.320 0.923
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
FGFR1 P11362 fibroblast growth factor receptor 1 Kinase 1.00 0.362 0.885
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
PIK3CB P42338 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta Kinase 1.00 0.322 0.885
MAPK1 P28482 mitogen-activated protein kinase 1 Kinase 1.00 0.330 0.923
HIF1A Q16665 hypoxia inducible factor 1 subunit alpha Transcription factor 0.98 0.327 0.923
AKT1 P31749 AKT serine/threonine kinase 1 Kinase 0.98 0.311 0.962
HMGA2 P52926 high mobility group AT-hook 2 Nucleic acid binding 0.87 0.429 0.808
TNF P01375 tumor necrosis factor Signaling 0.80 0.231 0.962
TIMM8A O60220 translocase of inner mitochondrial membrane 8A 0.65 0.510 0.846
ALB P02768 albumin Transporter 0.64 0.317 0.962
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
IGF1 P05019 insulin like growth factor 1 0.27 0.318 0.885
PTEN P60484 phosphatase and tensin homolog Enzyme 0.26 0.305 0.923
TNFSF10 P50591 TNF superfamily member 10 Signaling 0.13 0.413 0.885
IL1B P01584 interleukin 1 beta 0.13 0.276 0.962
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
SERPINE1 P05121 serpin family E member 1 Enzyme modulator 4.4E-02 0.359 0.885
TGFB1 P01137 transforming growth factor beta 1 Signaling 3.7E-02 0.287 0.962