Disease: Malignant transformation
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
HOXA9 P31269 homeobox A9 4.4E-05 0.521 0.692
IGF2R P11717 insulin like growth factor 2 receptor Receptor 1.00 0.518 0.731
IL2RB P14784 interleukin 2 receptor subunit beta Receptor 0.29 0.491 0.846
JAK2 O60674 Janus kinase 2 Kinase 0.65 0.385 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
LONP1 P36776 lon peptidase 1, mitochondrial Enzyme 1.00 0.517 0.808
MAP3K19 Q56UN5 mitogen-activated protein kinase kinase kinase 19 Kinase 1.8E-22 0.780 0.269
MBD2 Q9UBB5 methyl-CpG binding domain protein 2 Epigenetic regulator 0.35 0.466 0.846
MCL1 Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 0.96 0.430 0.808
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MLLT1 Q03111 MLLT1 super elongation complex subunit Nucleic acid binding 0.99 0.663 0.346
MTDH Q86UE4 metadherin 0.33 0.491 0.769
MXI1 P50539 MAX interactor 1, dimerization protein Transcription factor 1.1E-03 0.547 0.615
MYB P10242 MYB proto-oncogene, transcription factor 0.82 0.490 0.692
NLRP3 Q96P20 NLR family pyrin domain containing 3 8.1E-04 0.361 0.962
NOTCH1 P46531 notch receptor 1 1.00 0.369 0.885
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
PIM1 P11309 Pim-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.482 0.769
PLCL1 Q15111 phospholipase C like 1 (inactive) Enzyme 1.2E-02 0.608 0.654
PRDM16 Q9HAZ2 PR/SET domain 16 1.00 0.522 0.808
PTK2 Q05397 protein tyrosine kinase 2 Kinase 1.00 0.497 0.808
PVT1 Pvt1 oncogene 0.495 0.731
RARB P10826 retinoic acid receptor beta Nuclear receptor 1.00 0.478 0.846
RGS11 O94810 regulator of G protein signaling 11 7.3E-14 0.805 0.154
RNASEH2B Q5TBB1 ribonuclease H2 subunit B 3.3E-09 0.595 0.615