Disease: Malignant Peripheral Nerve Sheath Tumor
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846
BRCA1 P38398 BRCA1 DNA repair associated Enzyme 9.2E-29 0.367 0.923
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
CD274 Q9NZQ7 CD274 molecule Receptor 1.9E-02 0.324 0.923
CD44 P16070 CD44 molecule (Indian blood group) 2.4E-07 0.363 0.962
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
DCTN6 O00399 dynactin subunit 6 Cellular structure 5.6E-02 0.442 0.769
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
H3P23 H3 histone pseudogene 23 0.443 0.769
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
HMGA1 P17096 high mobility group AT-hook 1 Nucleic acid binding 0.83 0.494 0.769
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
KDR P35968 kinase insert domain receptor Kinase 1.00 0.378 0.885