Disease: Malignant Peripheral Nerve Sheath Tumor
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
H3P23 H3 histone pseudogene 23 0.443 0.769
PSMD9 O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 4.9E-06 0.435 0.846
PIK3CD O00329 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta Kinase 1.00 0.319 0.885
DCTN6 O00399 dynactin subunit 6 Cellular structure 5.6E-02 0.442 0.769
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
ZNRD2 O60232 zinc ribbon domain containing 2 1.8E-07 0.443 0.769
BRD4 O60885 bromodomain containing 4 Epigenetic regulator 1.00 0.446 0.885
TRIO O75962 trio Rho guanine nucleotide exchange factor Kinase 1.00 0.556 0.731
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923
EGF P01133 epidermal growth factor 8.5E-17 0.357 0.923
ESR1 P03372 estrogen receptor 1 Nuclear receptor 1.00 0.324 0.962
RAF1 P04049 Raf-1 proto-oncogene, serine/threonine kinase Kinase 0.85 0.418 0.885
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
IGF1R P08069 insulin like growth factor 1 receptor Kinase 0.97 0.399 0.885
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
HGF P14210 hepatocyte growth factor Enzyme 1.00 0.374 0.885
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846