Disease: Malignant Peripheral Nerve Sheath Tumor
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
TOP2A P11388 DNA topoisomerase II alpha 0.99 0.497 0.731
TRIO O75962 trio Rho guanine nucleotide exchange factor Kinase 1.00 0.556 0.731
HMGA1 P17096 high mobility group AT-hook 1 Nucleic acid binding 0.83 0.494 0.769
IFI27 P40305 interferon alpha inducible protein 27 1.1E-02 0.437 0.769
ZNRD2 O60232 zinc ribbon domain containing 2 1.8E-07 0.443 0.769
DCTN6 O00399 dynactin subunit 6 Cellular structure 5.6E-02 0.442 0.769
TICAM2 Q86XR7 Q9Y3B3 toll like receptor adaptor molecule 2 2.6E-03 0.438 0.769
TMED7-TICAM2 Q86XR7 Q9Y3B3 TMED7-TICAM2 readthrough 2.6E-03 0.438 0.769
H3P23 H3 histone pseudogene 23 0.443 0.769
KIT P10721 KIT proto-oncogene, receptor tyrosine kinase Kinase 0.98 0.366 0.808
MCL1 Q07820 MCL1 apoptosis regulator, BCL2 family member Signaling 0.96 0.430 0.808
MYCN P04198 MYCN proto-oncogene, bHLH transcription factor Transcription factor 0.89 0.454 0.808
NRAS P01111 NRAS proto-oncogene, GTPase Enzyme modulator 0.49 0.390 0.808
PDGFRA P16234 platelet derived growth factor receptor alpha Kinase 1.00 0.415 0.808
MAP2K7 O14733 mitogen-activated protein kinase kinase 7 Kinase 1.00 0.419 0.808
TMED7 Q86XR7 Q9Y3B3 transmembrane p24 trafficking protein 7 Transporter 0.48 0.436 0.808
BRAF P15056 B-Raf proto-oncogene, serine/threonine kinase Kinase 1.00 0.319 0.846
BRCA2 P51587 BRCA2 DNA repair associated Nucleic acid binding 2.4E-25 0.379 0.846
ERBB4 Q15303 erb-b2 receptor tyrosine kinase 4 Kinase 1.00 0.455 0.846
MDM2 Q00987 MDM2 proto-oncogene Nucleic acid binding 1.00 0.362 0.846
MET P08581 MET proto-oncogene, receptor tyrosine kinase Kinase 0.97 0.380 0.846
PSMD9 O00233 proteasome 26S subunit, non-ATPase 9 Enzyme modulator 4.9E-06 0.435 0.846
BECN1 Q14457 beclin 1 Enzyme modulator 0.94 0.432 0.846
BCL2 P10415 BCL2 apoptosis regulator Signaling 0.56 0.291 0.885
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885