Disease: Hereditary Nonpolyposis Colorectal Cancer
Source: ALL
Gene Uniprot Gene Full Name Protein Class pLI DSI v DPI v
APC P25054 APC regulator of WNT signaling pathway 1.00 0.373 0.962
PIK3CA P42336 phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha Kinase 1.00 0.292 0.923
ARID1A O14497 AT-rich interaction domain 1A 1.00 0.455 0.846
CTNNB1 P35222 catenin beta 1 1.00 0.303 0.885
SMAD4 Q13485 SMAD family member 4 Transcription factor 1.00 0.401 0.808
MYC P01106 MYC proto-oncogene, bHLH transcription factor Transcription factor 1.00 0.344 0.923
PTGS2 P35354 prostaglandin-endoperoxide synthase 2 Enzyme 1.00 0.314 0.962
KLF6 Q99612 Kruppel like factor 6 Nucleic acid binding 0.98 0.501 0.846
CTNNA1 P35221 catenin alpha 1 Cellular structure 0.97 0.584 0.538
MRC1 P22897 mannose receptor C-type 1 0.94 0.413 0.846
CCND1 P24385 cyclin D1 Enzyme modulator 0.89 0.344 0.923
RNF43 Q68DV7 ring finger protein 43 0.73 0.584 0.577
CDKN1B P46527 cyclin dependent kinase inhibitor 1B 0.62 0.409 0.769
TP53 P04637 tumor protein p53 Transcription factor 0.53 0.236 0.962
CDX2 Q99626 caudal type homeobox 2 Transcription factor 0.53 0.458 0.769
GREM1 O60565 gremlin 1, DAN family BMP antagonist 0.47 0.508 0.808
CDKN2A P42771 Q8N726 cyclin dependent kinase inhibitor 2A 0.39 0.300 0.885
EGFR P00533 epidermal growth factor receptor Kinase 0.37 0.295 0.885
DNMT3B Q9UBC3 DNA methyltransferase 3 beta 0.20 0.453 0.846
CDH1 P12830 cadherin 1 0.15 0.401 0.808
TGFBR2 P37173 transforming growth factor beta receptor 2 Kinase 0.13 0.413 0.846
HRAS P01112 HRas proto-oncogene, GTPase Enzyme modulator 8.0E-02 0.378 0.885
GSTP1 P09211 glutathione S-transferase pi 1 1.4E-02 0.383 0.923
ERBB2 P04626 erb-b2 receptor tyrosine kinase 2 Kinase 6.0E-03 0.328 0.923
KRAS P01116 KRAS proto-oncogene, GTPase Enzyme modulator 7.9E-04 0.320 0.923